Detailed information NTG0412044

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GKS41_RS19355
• Genome accession: NZ_CP047268
• Coordinates: 3891078..3892241 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain DH8043
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3886078..3897241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKS41_RS19325	-	3886343..3886762 (-)	420	WP_061861586.1	TIGR03826 family flagellar region protein	-
GKS41_RS19330	comFC	3886836..3887525 (-)	690	WP_201448519.1	phosphoribosyltransferase family protein	Machinery gene
GKS41_RS19335	-	3887531..3887815 (-)	285	WP_159354645.1	late competence development ComFB family protein	-
GKS41_RS19340	comFA	3887873..3889258 (-)	1386	WP_159354646.1	DEAD/DEAH box helicase	Machinery gene
GKS41_RS19345	-	3889366..3890214 (-)	849	WP_003151387.1	DegV family protein	-
GKS41_RS19350	degU	3890312..3891001 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GKS41_RS19355	degS	3891078..3892241 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GKS41_RS19360	-	3892464..3893111 (+)	648	WP_007614107.1	YigZ family protein	-
GKS41_RS19365	-	3893116..3894147 (+)	1032	Protein_3808	LCP family protein	-
GKS41_RS19370	-	3894487..3896286 (-)	1800	WP_159354647.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=412044 GKS41_RS19355 WP_007407484.1 3891078..3892241(-) (degS) [Bacillus velezensis strain DH8043]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=412044 GKS41_RS19355 WP_007407484.1 3891078..3892241(-) (degS) [Bacillus velezensis strain DH8043]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGAAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCAGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGCCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGATAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951