Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GQY29_RS07605 Genome accession   NZ_CP047191
Coordinates   1435076..1436416 (+) Length   446 a.a.
NCBI ID   WP_084828862.1    Uniprot ID   A0A0E2Q0P2
Organism   Streptococcus thermophilus strain EU01     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1430076..1441416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQY29_RS07580 (GQY29_07580) - 1430859..1431509 (-) 651 WP_100273221.1 amino acid ABC transporter permease -
  GQY29_RS07585 (GQY29_07585) - 1431521..1432219 (-) 699 WP_014608374.1 amino acid ABC transporter permease -
  GQY29_RS07590 (GQY29_07590) - 1432237..1433070 (-) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  GQY29_RS07595 (GQY29_07595) - 1433082..1433849 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  GQY29_RS07600 (GQY29_07600) vicR 1434376..1435083 (+) 708 WP_011681206.1 response regulator YycF Regulator
  GQY29_RS07605 (GQY29_07605) vicK 1435076..1436416 (+) 1341 WP_084828862.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GQY29_RS07610 (GQY29_07610) vicX 1436425..1437234 (+) 810 WP_024704147.1 MBL fold metallo-hydrolase Regulator
  GQY29_RS07615 (GQY29_07615) - 1437294..1437645 (+) 352 Protein_1415 YbaN family protein -
  GQY29_RS07620 (GQY29_07620) - 1437697..1438911 (-) 1215 WP_084828861.1 aminoacyltransferase -
  GQY29_RS07625 (GQY29_07625) yidA 1438913..1439722 (-) 810 WP_011226081.1 sugar-phosphatase -
  GQY29_RS07630 (GQY29_07630) - 1439930..1440856 (+) 927 Protein_1418 GNAT family N-acetyltransferase -
  GQY29_RS07635 (GQY29_07635) - 1440914..1441300 (+) 387 WP_159341046.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50777.01 Da        Isoelectric Point: 5.2465

>NTDB_id=411411 GQY29_RS07605 WP_084828862.1 1435076..1436416(+) (vicK) [Streptococcus thermophilus strain EU01]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGQITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=411411 GQY29_RS07605 WP_084828862.1 1435076..1436416(+) (vicK) [Streptococcus thermophilus strain EU01]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGCAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment