Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GQY29_RS01280 Genome accession   NZ_CP047191
Coordinates   248869..249558 (-) Length   229 a.a.
NCBI ID   WP_159340917.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EU01     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 243869..254558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQY29_RS01260 (GQY29_01260) dnaI 244676..245578 (-) 903 WP_011680740.1 primosomal protein DnaI -
  GQY29_RS01265 (GQY29_01265) - 245582..246757 (-) 1176 WP_011680739.1 DnaD domain protein -
  GQY29_RS01270 (GQY29_01270) nrdR 246754..247233 (-) 480 WP_011680738.1 transcriptional regulator NrdR -
  GQY29_RS01275 (GQY29_01275) covS 247355..248872 (-) 1518 WP_002949640.1 HAMP domain-containing histidine kinase Regulator
  GQY29_RS01280 (GQY29_01280) covR 248869..249558 (-) 690 WP_159340917.1 response regulator transcription factor Regulator
  GQY29_RS01285 (GQY29_01285) - 249714..250250 (-) 537 WP_002946488.1 YceD family protein -
  GQY29_RS01290 (GQY29_01290) rsmG 250547..251260 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GQY29_RS01295 (GQY29_01295) - 251330..252694 (+) 1365 WP_084825618.1 potassium transporter TrkG -
  GQY29_RS01300 (GQY29_01300) - 252734..253405 (+) 672 WP_002946492.1 TrkA family potassium uptake protein -
  GQY29_RS10525 - 253422..253592 (-) 171 Protein_249 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26671.83 Da        Isoelectric Point: 4.7059

>NTDB_id=411369 GQY29_RS01280 WP_159340917.1 248869..249558(-) (covR) [Streptococcus thermophilus strain EU01]
MCKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=411369 GQY29_RS01280 WP_159340917.1 248869..249558(-) (covR) [Streptococcus thermophilus strain EU01]
ATGTGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACTTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment