Detailed information NTG0410669

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GE573_RS07110
• Genome accession: NZ_CP047119
• Coordinates: 1368853..1370016 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AK-0
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1363853..1375016

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE573_RS07080 (GE573_01413)	-	1364118..1364537 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
GE573_RS07085	comFC	1364611..1365300 (-)	690	WP_206583745.1	ComF family protein	Machinery gene
GE573_RS07090 (GE573_01415)	-	1365306..1365590 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
GE573_RS07095 (GE573_01416)	comFA	1365648..1367033 (-)	1386	WP_190664622.1	DEAD/DEAH box helicase	Machinery gene
GE573_RS07100 (GE573_01417)	-	1367141..1367989 (-)	849	WP_063094272.1	DegV family protein	-
GE573_RS07105 (GE573_01418)	degU	1368087..1368776 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GE573_RS07110 (GE573_01419)	degS	1368853..1370016 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GE573_RS07115 (GE573_01420)	-	1370239..1370886 (+)	648	WP_061581228.1	YigZ family protein	-
GE573_RS07120 (GE573_01421)	-	1370891..1372111 (+)	1221	WP_061581227.1	LCP family protein	-
GE573_RS07125 (GE573_01422)	-	1372210..1373286 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
GE573_RS07130 (GE573_01423)	tuaH	1373419..1374615 (-)	1197	WP_069006925.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=410669 GE573_RS07110 WP_007407484.1 1368853..1370016(-) (degS) [Bacillus velezensis strain AK-0]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=410669 GE573_RS07110 WP_007407484.1 1368853..1370016(-) (degS) [Bacillus velezensis strain AK-0]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951