Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GPZ88_RS02545 Genome accession   NZ_CP046919
Coordinates   484289..484981 (-) Length   230 a.a.
NCBI ID   WP_006532917.1    Uniprot ID   A0A380KNN3
Organism   Streptococcus ruminicola strain CNU_G2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 479289..489981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS02525 (GPZ88_02505) dnaI 480098..481000 (-) 903 WP_074560813.1 primosomal protein DnaI -
  GPZ88_RS02530 (GPZ88_02510) - 481011..482162 (-) 1152 WP_157629322.1 DnaD domain protein -
  GPZ88_RS02535 (GPZ88_02515) nrdR 482149..482643 (-) 495 WP_074560815.1 transcriptional regulator NrdR -
  GPZ88_RS02540 (GPZ88_02520) - 482802..484184 (-) 1383 WP_238385866.1 sensor histidine kinase -
  GPZ88_RS02545 (GPZ88_02525) covR 484289..484981 (-) 693 WP_006532917.1 response regulator transcription factor Regulator
  GPZ88_RS02550 (GPZ88_02530) - 485221..485757 (-) 537 WP_166043286.1 YceD family protein -
  GPZ88_RS02555 (GPZ88_02535) htpX 485899..486798 (-) 900 WP_039696378.1 zinc metalloprotease HtpX -
  GPZ88_RS02560 (GPZ88_02540) - 486911..487462 (-) 552 WP_014335211.1 LemA family protein -
  GPZ88_RS02565 (GPZ88_02545) rsmG 487752..488465 (+) 714 WP_074564313.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GPZ88_RS02570 (GPZ88_02550) - 488541..489914 (+) 1374 WP_074626245.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26400.31 Da        Isoelectric Point: 4.7654

>NTDB_id=409399 GPZ88_RS02545 WP_006532917.1 484289..484981(-) (covR) [Streptococcus ruminicola strain CNU_G2]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=409399 GPZ88_RS02545 WP_006532917.1 484289..484981(-) (covR) [Streptococcus ruminicola strain CNU_G2]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACTGCATTGGATGATGATTTTGATTTGATCCTATTAGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGACACTTCAATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTACATTGTAAAACCATTTGCTATTGA
AGAATTACTCGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGACAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCTGCAGTGCGTGGTGATGATGAAATTTCATTAACAAAACGT
GAATACGATTTGTTGAGCGTGCTTCTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATCGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KNN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.087

100

0.761
  covR Lactococcus lactis subsp. lactis strain DGCC12653

64.192

99.565

0.639
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417
  vicR Streptococcus mutans UA159

41.558

100

0.417

Multiple sequence alignment