Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GP482_RS05525 Genome accession   NZ_CP046875
Coordinates   1136874..1138226 (-) Length   450 a.a.
NCBI ID   WP_039696510.1    Uniprot ID   A0AAE6UZR7
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1131874..1143226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS05515 (GP482_05515) rnc 1135156..1135842 (-) 687 WP_020917219.1 ribonuclease III -
  GP482_RS05520 (GP482_05520) vicX 1136064..1136873 (-) 810 WP_074602529.1 MBL fold metallo-hydrolase Regulator
  GP482_RS05525 (GP482_05525) vicK 1136874..1138226 (-) 1353 WP_039696510.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GP482_RS05530 (GP482_05530) vicR 1138219..1138929 (-) 711 WP_039696509.1 response regulator YycF Regulator
  GP482_RS05535 (GP482_05535) - 1139241..1140005 (+) 765 WP_039696508.1 amino acid ABC transporter ATP-binding protein -
  GP482_RS05540 (GP482_05540) - 1140016..1140828 (+) 813 WP_158914293.1 transporter substrate-binding domain-containing protein -
  GP482_RS05545 (GP482_05545) - 1140844..1141551 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  GP482_RS05550 (GP482_05550) - 1141564..1142211 (+) 648 WP_157629243.1 amino acid ABC transporter permease -
  GP482_RS05555 (GP482_05555) - 1142249..1142857 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51378.34 Da        Isoelectric Point: 4.7359

>NTDB_id=409123 GP482_RS05525 WP_039696510.1 1136874..1138226(-) (vicK) [Streptococcus ruminicola strain CNU_77-61]
MNDTMVQNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=409123 GP482_RS05525 WP_039696510.1 1136874..1138226(-) (vicK) [Streptococcus ruminicola strain CNU_77-61]
ATGAATGATACAATGGTACAGAATCAATATCTGTTTGAACAAGCCATTCTTTTCTTGTTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGTCGATTGAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGACAGAGATTTAGCAGAGCTGGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTGGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTAGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGGATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGCGATGAGACGGGAGAATTTATCACTTTGCGCATTCGTTTCGCCTTAAATCGTAGAGATAGTGG
TTTTATTTCTGGGCTGATTGCTGTCTTGCATGATACGACAGAGCAAGAAAAAGAAGACCGTGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAATTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAGGCACTGGATGAAGGGGCTCTGAAA
GAAGATATTGCACCAAGTTTCATTAAAGTTTCTTTGGATGAAACCAACCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTAGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACGAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAGAGCCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCGATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACACAGGTCTTGGATAATATCCTAAATAATGCCATTAAGTATTCACCAGA
CGGTGGTAAAATTACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.237

97.556

0.627

Multiple sequence alignment