Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GP482_RS05530 Genome accession   NZ_CP046875
Coordinates   1138219..1138929 (-) Length   236 a.a.
NCBI ID   WP_039696509.1    Uniprot ID   A0A6G8HYC0
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1133219..1143929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS05515 (GP482_05515) rnc 1135156..1135842 (-) 687 WP_020917219.1 ribonuclease III -
  GP482_RS05520 (GP482_05520) vicX 1136064..1136873 (-) 810 WP_074602529.1 MBL fold metallo-hydrolase Regulator
  GP482_RS05525 (GP482_05525) vicK 1136874..1138226 (-) 1353 WP_039696510.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GP482_RS05530 (GP482_05530) vicR 1138219..1138929 (-) 711 WP_039696509.1 response regulator YycF Regulator
  GP482_RS05535 (GP482_05535) - 1139241..1140005 (+) 765 WP_039696508.1 amino acid ABC transporter ATP-binding protein -
  GP482_RS05540 (GP482_05540) - 1140016..1140828 (+) 813 WP_158914293.1 transporter substrate-binding domain-containing protein -
  GP482_RS05545 (GP482_05545) - 1140844..1141551 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  GP482_RS05550 (GP482_05550) - 1141564..1142211 (+) 648 WP_157629243.1 amino acid ABC transporter permease -
  GP482_RS05555 (GP482_05555) - 1142249..1142857 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -
  GP482_RS05560 (GP482_05560) - 1143070..1143372 (-) 303 WP_157629244.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27121.90 Da        Isoelectric Point: 4.7040

>NTDB_id=409124 GP482_RS05530 WP_039696509.1 1138219..1138929(-) (vicR) [Streptococcus ruminicola strain CNU_77-61]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=409124 GP482_RS05530 WP_039696509.1 1138219..1138929(-) (vicR) [Streptococcus ruminicola strain CNU_77-61]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAACTTAACTAAAGAAGGTTATGA
AACTGTTACGGCTTTTGATGGTCGTGAAGCAATTGCTAAATTTGAAGAAGAAAATCCTGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTTGCAAAAGAAGTTCGTAAAACAAGTCATATTCCGATTATTATGCTTTCTGCT
AAAGATAGCGAGTTCGATAAAGTTATCGGTCTTGAAATCGGTGCAGATGACTACGTTACAAAACCTTTCTCAAATCGTGA
ATTGTTAGCACGTGTCAAAGCACACCTTCGTCGTACTGAGAACATCGAATCAGCCGTCGCTGAGGAAAATGCTTCTTCAT
CAAATTCTGAAATTACCATCGGCGATTTGAAGATTTTGCCTGATGCCTTTGTTGCCCAAAAACGTGGCGAAGACATTGAA
TTAACACACCGTGAATTTGAATTACTTCATCACTTAGCTACTCACATGGGACAAGTGATGACGCGTGAATACCTTTTGGA
GACTGTTTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTTGACGTTACCATCCGTCGTTTACGTGAAAAAATCGAAG
ACACTCCGAGCCGTCCAGAATACATTTTGACACGTCGCGGTGTTGGATACTACATGAAGTCTTATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HYC0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.205

99.153

0.775
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

36.441

100

0.364

Multiple sequence alignment