Detailed information NTG0406313

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GPA00_RS05970
• Genome accession: NZ_CP046629
• Coordinates: 1178811..1181042 (+)
• Length: 743 a.a.
• NCBI ID: WP_157327857.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1173811..1186042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS05940 (GPA00_05940)	-	1174386..1175252 (+)	867	WP_157327851.1	helix-turn-helix transcriptional regulator	-
GPA00_RS05945 (GPA00_05945)	-	1175262..1176152 (+)	891	WP_157327853.1	ROK family protein	-
GPA00_RS05950 (GPA00_05950)	-	1176167..1176442 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
GPA00_RS05955 (GPA00_05955)	-	1176417..1177178 (-)	762	WP_074450932.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GPA00_RS05960 (GPA00_05960)	-	1177297..1178043 (+)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
GPA00_RS05965 (GPA00_05965)	comEA	1178138..1178818 (+)	681	WP_157327855.1	helix-hairpin-helix domain-containing protein	Machinery gene
GPA00_RS05970 (GPA00_05970)	comEC/celB	1178811..1181042 (+)	2232	WP_157327857.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GPA00_RS05975 (GPA00_05975)	holA	1181110..1182147 (+)	1038	WP_074479778.1	DNA polymerase III subunit delta	-
GPA00_RS05980 (GPA00_05980)	sodA	1182243..1182854 (+)	612	WP_039698404.1	superoxide dismutase SodA	-
GPA00_RS05985 (GPA00_05985)	-	1182960..1183685 (+)	726	WP_024344280.1	YebC/PmpR family DNA-binding transcriptional regulator	-
GPA00_RS05990 (GPA00_05990)	queA	1183732..1184760 (-)	1029	WP_021141922.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
GPA00_RS05995 (GPA00_05995)	-	1184920..1185426 (+)	507	WP_033152227.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83875.54 Da
• Isoelectric Point: 9.5282

>NTDB_id=406313 GPA00_RS05970 WP_157327857.1 1178811..1181042(+) (comEC/celB) [Streptococcus equinus strain CNU G6]
MIKHFPIKPIQLAFLLILVYYFCFLKVFWCIVLLLLALVCLWKNYGSKKLWQTLIILMCFASFISFKNQQAEQADKVAPA
HLSKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYTLKSEKEQQFFKSLNQTLVLFGEIDLEKATPQRNFGGFDYRTYLKH
EGIYRIGNLSSIVGMRRQTSLTLVERLHDLRRKAIVSIQQNFPAPMRHYMTGLLFGYLDKSFDEMSDIYTSLGIIHLFAL
SGMQVGFFVSVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSGLGNIGVKRLDNLALTMMILFSIMPN
FLLTTGGILSFAYAFILSFIDFEELESYQKKIVECLAISLGSLPILLYFFSVFQPMSILLTAIFSLAFDTLMLPVLSVVL
LLSPLVRLSIFNSFFIVLEDVIKLTMNFLGGPIVFGKPSIGILVFLLFSLGVLYDYRQKRKVMIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGRTLLIDVGGKVSFSQKEGWQERLSDSNADRTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEVLVSQGSLTKPDFVAKLQAMKTKVRIVSAGDSLPIMGSSLQVLYPIRVGDGSNNDSVVLYGKLLGK
NFLFTGDLEEEGEREVMATYPNLPVDVLKAGHHGSKGSSSPAFLAHISPQIALISAGQNNRYKHPHQETLERFQAQNMTI
YRTDEQGAIRFRGLKHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=406313 GPA00_RS05970 WP_157327857.1 1178811..1181042(+) (comEC/celB) [Streptococcus equinus strain CNU G6]
TTGATTAAACATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTCTCGTTTATTATTTTTGCTTTTTGAAGGT
CTTTTGGTGCATAGTCCTCCTTTTATTAGCCCTGGTCTGCTTATGGAAAAACTACGGTTCTAAAAAATTGTGGCAAACCT
TGATAATTCTGATGTGCTTTGCTAGTTTTATTAGTTTTAAAAATCAGCAAGCAGAGCAAGCTGACAAAGTAGCGCCAGCT
CATTTATCAAAAATCCAGATGATTCCAGACACGATTTCGGTCAATGGTGACTTGCTGTCTTTTCGAGGGAAGGAGGCTGG
ACAGACTTATCAGGTCTTTTATACTTTGAAGTCAGAAAAGGAGCAGCAATTTTTTAAAAGTCTTAATCAAACACTTGTCT
TGTTTGGTGAGATTGACTTGGAGAAAGCAACGCCTCAGCGTAATTTTGGTGGGTTTGACTATCGTACTTACCTGAAACAT
GAAGGTATTTATCGCATTGGGAATCTTTCTTCAATTGTTGGGATGAGACGTCAAACTTCTTTGACTTTGGTTGAGCGACT
GCATGATTTGCGACGAAAAGCAATTGTTAGCATCCAGCAAAATTTTCCAGCACCCATGCGACATTATATGACGGGGCTTT
TGTTTGGTTATCTGGATAAATCTTTTGATGAGATGAGCGATATTTACACGAGTTTAGGAATTATTCATCTTTTTGCTCTT
TCCGGTATGCAGGTTGGCTTTTTTGTCAGTGTTTTTCGCTATTTCTTTTTGCGACTAGGCTTAAGGCGTGATTATGTTGA
CATTCTTCAAATCCCTTTTTCGCTTGTATATGCTGGTCTGACAGGATTTTCAGTGTCAGTTGTCCGAAGTCTCATTCAGT
CAGGTTTAGGCAATATTGGCGTTAAGCGACTTGATAATCTTGCTTTGACCATGATGATTCTTTTCAGCATTATGCCTAAT
TTCCTGCTGACAACGGGAGGCATTTTGTCATTTGCTTATGCCTTTATCTTAAGTTTTATTGATTTTGAGGAACTTGAAAG
TTATCAGAAGAAAATTGTAGAATGCTTGGCAATTTCACTAGGTAGCTTACCAATTTTGCTTTACTTTTTTTCAGTTTTTC
AACCGATGTCCATTCTTTTGACAGCTATTTTTTCATTGGCATTTGATACGCTTATGTTGCCAGTCTTGTCAGTGGTTCTC
TTGCTTTCGCCACTCGTGAGATTATCAATTTTTAATAGCTTTTTTATCGTTTTAGAAGATGTGATAAAACTGACTATGAA
TTTCCTTGGTGGTCCGATTGTTTTTGGCAAACCAAGTATTGGTATTTTGGTATTCCTATTATTTAGCTTGGGTGTTCTTT
ATGATTATAGGCAGAAAAGGAAAGTTATGATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTCCAAATCAAGCATCCG
CTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCGTACGCTGTT
AATTGATGTCGGAGGAAAAGTGAGCTTTAGCCAAAAAGAAGGCTGGCAAGAGCGCTTGTCTGACAGCAATGCAGATCGAA
CCTTGATTCCTTATCTCAATAGCCGTGGCGTTGGAAAAATTGACCAGCTGGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAGTTTTGGTTAGTCAAGGAAGTTTGACAAAGCCAGATTT
TGTGGCAAAATTACAAGCAATGAAAACCAAGGTTCGCATAGTTTCTGCTGGAGATAGTCTGCCGATTATGGGAAGTAGCT
TGCAGGTACTGTACCCTATTAGAGTTGGCGATGGTTCTAATAATGATTCGGTGGTGTTGTATGGCAAACTTCTTGGTAAA
AATTTTCTGTTTACAGGAGATTTGGAAGAAGAAGGCGAGCGTGAGGTGATGGCGACTTATCCTAATTTGCCAGTTGATGT
TTTAAAAGCGGGACACCATGGCTCAAAAGGTTCATCAAGCCCGGCATTTCTAGCTCATATTTCACCGCAGATTGCTCTGA
TTTCTGCAGGTCAAAATAACCGCTACAAACATCCTCACCAAGAAACGCTTGAACGATTTCAAGCGCAAAATATGACCATT
TACCGCACAGACGAACAAGGCGCCATCCGCTTTCGAGGCTTAAAACACTGGAAAATTGAGACGGTAAGGTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-696)

• Competence protein (Competence) (213-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	52.426	99.865	0.524
comEC/celB	Streptococcus mitis NCTC 12261	52.022	99.865	0.52
comEC/celB	Streptococcus pneumoniae TIGR4	51.279	100	0.513
comEC/celB	Streptococcus pneumoniae Rx1	50.875	100	0.509
comEC/celB	Streptococcus pneumoniae D39	50.875	100	0.509
comEC/celB	Streptococcus pneumoniae R6	50.875	100	0.509
comEC	Lactococcus lactis subsp. cremoris KW2	46.595	100	0.47