Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GPA00_RS05315 Genome accession   NZ_CP046629
Coordinates   1052243..1053541 (+) Length   432 a.a.
NCBI ID   WP_157327770.1    Uniprot ID   -
Organism   Streptococcus equinus strain CNU G6     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1047243..1058541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS05290 (GPA00_05290) - 1047936..1048580 (+) 645 WP_024344653.1 response regulator transcription factor -
  GPA00_RS05295 (GPA00_05295) - 1048704..1050104 (+) 1401 WP_029876003.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GPA00_RS05300 (GPA00_05300) - 1050104..1050460 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -
  GPA00_RS05305 (GPA00_05305) cysK 1050535..1051464 (-) 930 WP_157327768.1 cysteine synthase A -
  GPA00_RS05310 (GPA00_05310) - 1051562..1052188 (-) 627 WP_024344657.1 YigZ family protein -
  GPA00_RS05315 (GPA00_05315) comFA/cflA 1052243..1053541 (+) 1299 WP_157327770.1 DEAD/DEAH box helicase Machinery gene
  GPA00_RS05320 (GPA00_05320) - 1053541..1054206 (+) 666 WP_157327772.1 ComF family protein -
  GPA00_RS05325 (GPA00_05325) hpf 1054283..1054831 (+) 549 WP_024344660.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49158.32 Da        Isoelectric Point: 9.4749

>NTDB_id=406309 GPA00_RS05315 WP_157327770.1 1052243..1053541(+) (comFA/cflA) [Streptococcus equinus strain CNU G6]
MEDKNDYYGRIFVESQLSDELKEEAEKLPSMVKRKDNFTCNRCGSIVLPDNILQTGQTYCRECLVFGRNISDSYLYYFPQ
KSFPKNNSLNWQGQLTPYQNEVSEGMLSGIAEKKDLLVHAVTGAGKTEMIYHSVAKIIDDGGCVCIASPRIDVCLELYKR
MSRDFSCPITLLHGEAEPYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNKMLYYAVNQSLKKDGVKIFLTATST
DELDKKVRKGDLKKLHLARRFHANPLVVPKMLWLSGVLKSMKKGKIPKKLNLLLKNQRKAGYPLLIFFPNIEQGKRFSMV
LQEKFPTEKIGFVSSQTEDRLELVEKFRKNEITILVSTTILERGVTFPCVDVFVILANHKLYTKSALVQISGRVGRAAER
PTGELLFLHDGATKSMQQAIKEIKEMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=406309 GPA00_RS05315 WP_157327770.1 1052243..1053541(+) (comFA/cflA) [Streptococcus equinus strain CNU G6]
ATGGAAGATAAAAATGACTATTATGGAAGAATTTTTGTTGAGTCTCAATTGTCTGATGAGTTAAAAGAAGAAGCTGAAAA
ACTTCCTTCTATGGTAAAAAGAAAAGACAATTTTACGTGTAACCGCTGCGGAAGCATTGTTTTACCAGATAATATTTTAC
AAACTGGTCAGACTTACTGCAGAGAATGTCTAGTTTTTGGTCGTAACATCAGTGATTCTTATCTATATTACTTTCCGCAA
AAAAGTTTTCCAAAAAATAATTCTCTAAACTGGCAAGGGCAACTTACCCCTTATCAAAATGAAGTGTCAGAAGGTATGTT
GTCAGGAATTGCTGAAAAGAAAGATTTATTAGTTCATGCTGTGACAGGAGCTGGTAAGACAGAGATGATTTATCACTCAG
TAGCAAAAATAATCGATGATGGTGGTTGTGTTTGTATTGCTAGCCCACGAATTGATGTTTGTTTAGAACTTTATAAACGT
ATGTCTCGTGATTTTTCATGTCCGATTACTTTATTACATGGGGAAGCTGAGCCTTACAAACGAGCACCGCTCATTATTGC
AACAACTCATCAACTTTTAAAATTCTATCAAGCATTTGATTTATTAATCATCGATGAAGTTGATGCTTTTCCATTTGTTG
ACAATAAAATGCTGTATTACGCAGTAAATCAATCTTTAAAAAAAGATGGTGTCAAAATATTTTTAACAGCTACATCGACA
GATGAATTAGATAAAAAAGTTCGAAAAGGCGACTTAAAAAAATTGCATTTAGCCAGACGTTTTCACGCCAATCCTTTGGT
TGTTCCTAAAATGCTCTGGCTTAGTGGGGTGTTAAAGTCAATGAAAAAAGGAAAAATACCTAAAAAATTGAACTTGCTGC
TTAAAAATCAAAGAAAAGCAGGATATCCCTTACTAATCTTTTTTCCAAATATAGAGCAGGGAAAAAGATTTTCGATGGTT
CTGCAAGAAAAATTTCCTACTGAGAAGATTGGTTTTGTGTCAAGTCAGACCGAAGATAGACTTGAATTAGTTGAAAAATT
TAGAAAGAACGAAATAACAATTTTAGTAAGCACAACCATCTTAGAACGTGGGGTCACATTTCCTTGTGTTGACGTATTTG
TCATATTAGCAAATCATAAATTATACACTAAAAGTGCTCTTGTACAAATTTCTGGGCGAGTCGGTAGAGCTGCTGAACGA
CCAACAGGAGAATTATTATTTTTGCACGATGGCGCTACAAAATCTATGCAACAAGCGATTAAAGAAATAAAGGAAATGAA
CAAGAAAGGAGGATTTTGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(96-244)

Helicase conserved C-terminal domain (Helicase_C)

(290-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

62.763

98.843

0.62
  comFA/cflA Streptococcus pneumoniae D39

62.763

98.843

0.62
  comFA/cflA Streptococcus pneumoniae R6

62.763

98.843

0.62
  comFA/cflA Streptococcus pneumoniae TIGR4

62.763

98.843

0.62
  comFA/cflA Streptococcus mitis NCTC 12261

61.111

100

0.611
  comFA/cflA Streptococcus mitis SK321

60.648

100

0.606
  comFA Lactococcus lactis subsp. cremoris KW2

51.523

91.204

0.47
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

100

0.37
  comFA Bacillus subtilis subsp. subtilis str. 168

36.054

100

0.368

Multiple sequence alignment