Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GPA00_RS01285 Genome accession   NZ_CP046629
Coordinates   252498..253190 (-) Length   230 a.a.
NCBI ID   WP_021143010.1    Uniprot ID   A0A239R7J1
Organism   Streptococcus equinus strain CNU G6     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 247498..258190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS01265 (GPA00_01265) dnaI 248307..249209 (-) 903 WP_024343628.1 primosomal protein DnaI -
  GPA00_RS01270 (GPA00_01270) - 249220..250371 (-) 1152 WP_157327211.1 DnaD domain protein -
  GPA00_RS01275 (GPA00_01275) nrdR 250358..250852 (-) 495 WP_004233042.1 transcriptional regulator NrdR -
  GPA00_RS01280 (GPA00_01280) - 251011..252393 (-) 1383 WP_232524219.1 ATP-binding protein -
  GPA00_RS01285 (GPA00_01285) covR 252498..253190 (-) 693 WP_021143010.1 response regulator transcription factor Regulator
  GPA00_RS01290 (GPA00_01290) - 253430..253966 (-) 537 WP_157327215.1 YceD family protein -
  GPA00_RS01295 (GPA00_01295) htpX 254115..255014 (-) 900 WP_157328503.1 zinc metalloprotease HtpX -
  GPA00_RS01300 (GPA00_01300) - 255131..255682 (-) 552 WP_021143013.1 LemA family protein -
  GPA00_RS01305 (GPA00_01305) rsmG 255977..256690 (+) 714 WP_024343622.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GPA00_RS01310 (GPA00_01310) ktrB 256756..258129 (+) 1374 WP_157327217.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26437.38 Da        Isoelectric Point: 4.8639

>NTDB_id=406271 GPA00_RS01285 WP_021143010.1 252498..253190(-) (covR) [Streptococcus equinus strain CNU G6]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQEANSKHDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=406271 GPA00_RS01285 WP_021143010.1 252498..253190(-) (covR) [Streptococcus equinus strain CNU G6]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTGGAGTTACAACACGAAGGGTA
TTCAGTAGTTGTTGAGACAAATGGGCGTTTAGGTTTACAAACGGCTTTAGATGATGATTTTGATTTGATCCTGTTGGACT
TGATGTTGCCTGATATGGATGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGAAACTTCAATTATCATGATGACA
GCTCGTGATTCAATCATGGATATTGTTGCTGGTCTTGATCGTGGCGCAGATGATTACATTGTAAAACCATTTGCTATTGA
AGAATTACTAGCGCGTGTGCGTGCAGTGTTCCGTCGTCAAGAAGCTAATTCTAAACATGATAAAGAAGGCCAAGCAAAAG
AGGGGTTGCTAGGACTTCGTCTTAATCCACAAAATCGTTCTGCAGTTCGTGGAGACGATGAAATTTCGTTAACAAAACGC
GAATATGATTTGTTAAGTGTTCTTCTTTCAAACGTTAACCGAGTGATGACACGTGAAGAATTACTTGCAAGTGTTTGGCG
TTATGATACTGATATCGAAACAAACGTAGTGGATGTTTACATCCGTTATCTTCGTGGAAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACTGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239R7J1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment