Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GO596_RS04760 Genome accession   NZ_CP046628
Coordinates   955229..955921 (+) Length   230 a.a.
NCBI ID   WP_021143010.1    Uniprot ID   A0A239R7J1
Organism   Streptococcus equinus strain CNU 77-23     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 950229..960921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS04735 (GO596_04735) - 950291..951664 (-) 1374 WP_074628374.1 TrkH family potassium uptake protein -
  GO596_RS04740 (GO596_04740) rsmG 951730..952443 (-) 714 WP_157339296.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  GO596_RS04745 (GO596_04745) - 952738..953289 (+) 552 WP_021143013.1 LemA family protein -
  GO596_RS04750 (GO596_04750) htpX 953406..954305 (+) 900 WP_024343624.1 zinc metalloprotease HtpX -
  GO596_RS04755 (GO596_04755) - 954451..954987 (+) 537 WP_024343625.1 YceD family protein -
  GO596_RS04760 (GO596_04760) covR 955229..955921 (+) 693 WP_021143010.1 response regulator transcription factor Regulator
  GO596_RS04765 (GO596_04765) - 956026..957408 (+) 1383 WP_232516839.1 ATP-binding protein -
  GO596_RS04770 (GO596_04770) nrdR 957568..958062 (+) 495 WP_004233042.1 transcriptional regulator NrdR -
  GO596_RS04775 (GO596_04775) - 958049..959200 (+) 1152 WP_157339298.1 DnaD domain protein -
  GO596_RS04780 (GO596_04780) dnaI 959211..960113 (+) 903 WP_024343628.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26437.38 Da        Isoelectric Point: 4.8639

>NTDB_id=406246 GO596_RS04760 WP_021143010.1 955229..955921(+) (covR) [Streptococcus equinus strain CNU 77-23]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQEANSKHDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=406246 GO596_RS04760 WP_021143010.1 955229..955921(+) (covR) [Streptococcus equinus strain CNU 77-23]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTGGAACTACAACACGAAGGGTA
TTCAGTAGTTGTTGAGACAAATGGGCGTTTAGGTTTACAAACGGCTTTGGATGATGATTTTGATTTAATTCTGTTAGATT
TGATGTTGCCTGATATGGATGGATTCGAAATTACACGTCGTCTTCGTCTGGAAAAAGAAACTTCAATTATCATGATGACA
GCTCGTGATTCAATCATGGATATCGTTGCTGGTCTTGATCGTGGTGCAGATGATTACATCGTAAAACCATTTGCTATTGA
AGAATTACTAGCGCGTGTGCGTGCAGTGTTCCGTCGTCAAGAAGCTAATTCTAAACATGATAAAGAAGGCCAAGCAAAAG
AGGGGTTGCTAGGACTTCGTCTTAATCCACAAAATCGTTCTGCAGTTCGCGGAGACGATGAAATTTCATTAACAAAACGC
GAATATGATTTGTTAAGTGTTCTTCTTTCAAACGTTAACCGAGTGATGACACGTGAAGAATTACTTGCAAGTGTTTGGCG
TTATGATACTGATATCGAAACAAACGTAGTGGATGTTTACATCCGTTATCTTCGTGGAAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACTGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239R7J1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment