Detailed information NTG0406205

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GO596_RS00075
• Genome accession: NZ_CP046628
• Coordinates: 15098..17329 (-)
• Length: 743 a.a.
• NCBI ID: WP_157338997.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 10098..22329

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS00050 (GO596_00050)	-	10713..11219 (-)	507	WP_021141923.1	VIT1/CCC1 transporter family protein	-
GO596_RS00055 (GO596_00055)	queA	11379..12407 (+)	1029	WP_021141922.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
GO596_RS00060 (GO596_00060)	-	12454..13179 (-)	726	WP_024344280.1	YebC/PmpR family DNA-binding transcriptional regulator	-
GO596_RS00065 (GO596_00065)	sodA	13285..13896 (-)	612	WP_157338995.1	superoxide dismutase SodA	-
GO596_RS00070 (GO596_00070)	holA	13993..15030 (-)	1038	WP_157338996.1	DNA polymerase III subunit delta	-
GO596_RS00075 (GO596_00075)	comEC/celB	15098..17329 (-)	2232	WP_157338997.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GO596_RS00080 (GO596_00080)	comEA	17322..18002 (-)	681	WP_157338998.1	helix-hairpin-helix domain-containing protein	Machinery gene
GO596_RS00085 (GO596_00085)	-	18097..18843 (-)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
GO596_RS00090 (GO596_00090)	-	18962..19723 (+)	762	WP_074450932.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GO596_RS00095 (GO596_00095)	-	19698..19973 (+)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
GO596_RS00100 (GO596_00100)	-	19988..20878 (-)	891	WP_157338999.1	ROK family protein	-
GO596_RS00105 (GO596_00105)	-	20888..21754 (-)	867	WP_039691015.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83895.55 Da
• Isoelectric Point: 9.4699

>NTDB_id=406205 GO596_RS00075 WP_157338997.1 15098..17329(-) (comEC/celB) [Streptococcus equinus strain CNU 77-23]
MIKHFPIKPIQLAFLLILVYYFCFLKFFWCIVLLLLALICLWKNYGSKKLWQTLIILMCFAGFISFKNQQAEQADKVSPA
HLSKIQMIPDTILVNGDLLSFRGKESGQTYQVFYTLKSEKEQQFFKSLNQTLVLSGEIDLEKATPQRNFGGFDYRTYLKH
EGIYRIGNLSSIVGMRRQTSLTLVERLHDLRRKAIVSIQQNFPAPMQHYMTGLLFGYLDKSFDEMSDIYTSLGIIHLFAL
SGMQVGFFVGVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSGLGNIGVKRLDNLALTMMILFCIMPN
FLLTTGGILSFTYAFILSFIDFVELESYQKKIVECLAISLGSLPILIYFFSVFQPMSILLTAIFSLAFDTLMLPVLSVVF
LLSPLVRLSIFNSFFIVLEDVIKLTMNFLGGPIVFGKPSIGILVFLLFSLGILYDYRQKRKVMIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSQKEGWQERLSDSNADRTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEVLISQGSLTKPDFVAKLQAMKTKVRVVSAGDSLSIMGSSLQVLYPIRVGDGSNNDSVVLYGKLLGK
NFLFTGDLEEEGEREVMATYPNLPVDVLKAGHHGSKGSSSPAFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=406205 GO596_RS00075 WP_157338997.1 15098..17329(-) (comEC/celB) [Streptococcus equinus strain CNU 77-23]
TTGATTAAACATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTCTCGTTTATTATTTTTGCTTTTTAAAGTT
TTTTTGGTGCATAGTCCTCCTTTTATTAGCCCTGATCTGCTTATGGAAAAACTACGGTTCTAAAAAATTGTGGCAAACCT
TGATAATTCTGATGTGCTTTGCTGGTTTTATTAGTTTTAAAAATCAGCAAGCAGAGCAAGCTGACAAAGTATCGCCAGCT
CATTTATCAAAAATCCAGATGATTCCAGACACGATTTTGGTCAATGGTGACTTGCTGTCTTTTCGAGGAAAGGAGTCTGG
ACAGACTTATCAGGTCTTTTATACTTTGAAGTCAGAAAAGGAGCAGCAATTTTTTAAAAGTCTTAATCAAACGCTTGTCT
TGTCTGGTGAGATTGACTTGGAGAAAGCAACGCCTCAGCGTAATTTTGGTGGGTTTGACTATCGGACTTACTTGAAACAT
GAAGGTATTTATCGCATTGGGAATCTTTCTTCAATTGTTGGGATGAGACGTCAAACTTCTTTGACTTTGGTTGAGCGACT
GCATGATTTGCGACGAAAAGCAATTGTTAGCATCCAGCAAAATTTTCCAGCACCCATGCAGCATTATATGACGGGGCTTT
TGTTTGGTTATCTGGATAAATCTTTTGATGAGATGAGCGATATTTACACGAGTTTGGGGATTATTCACCTCTTTGCTCTT
TCCGGTATGCAGGTTGGCTTTTTTGTCGGTGTTTTTCGCTATTTCTTTTTGCGACTTGGCTTAAGGCGTGATTATGTTGA
TATTCTTCAAATTCCTTTTTCGCTTGTATATGCTGGTTTGACAGGATTTTCAGTGTCAGTTGTCCGAAGTCTCATTCAGT
CAGGTTTAGGCAATATTGGCGTTAAGCGACTTGATAATCTTGCTTTGACCATGATGATTCTTTTCTGCATTATGCCTAAT
TTCCTGCTGACAACGGGAGGCATTTTGTCATTTACTTATGCCTTTATTCTAAGTTTTATTGATTTTGTGGAACTTGAAAG
TTATCAGAAGAAAATTGTAGAATGCTTGGCAATTTCATTAGGTAGCTTACCAATTTTGATTTACTTTTTTTCAGTTTTTC
AACCGATGTCTATTCTTTTGACAGCTATTTTTTCATTGGCATTTGATACTCTTATGTTGCCAGTCTTGTCAGTGGTTTTC
TTGCTTTCGCCACTCGTGAGATTATCAATTTTTAATAGCTTTTTTATCGTTTTAGAAGATGTGATAAAGCTGACTATGAA
TTTTCTTGGGGGTCCGATTGTTTTTGGCAAACCAAGTATTGGTATTTTGGTATTCCTATTATTTAGCTTAGGTATTCTTT
ATGATTACAGACAGAAAAGGAAAGTTATGATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTCCAAATCAAGCATCCG
CTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCATACGCTGTT
AATTGATGTCGGAGGAAAAGTGAGTTTTAGCCAAAAAGAAGGCTGGCAGGAGCGTTTGTCTGACAGTAATGCAGATCGAA
CCTTGATTCCTTATCTCAATAGCCGTGGCGTTGGAAAAATTGACCAGCTGGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAGTTTTGATTAGTCAAGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAAGTTCGCGTAGTTTCTGCTGGAGATAGTCTGTCGATTATGGGAAGTAGCT
TGCAGGTGCTTTATCCTATTAGAGTTGGCGATGGTTCTAATAATGATTCGGTGGTTTTGTATGGAAAGCTTCTAGGTAAA
AATTTTTTGTTTACAGGAGATTTGGAAGAAGAAGGTGAGCGTGAGGTGATGGCGACTTATCCTAATTTGCCAGTTGATGT
TTTAAAAGCGGGACACCATGGCTCAAAAGGGTCATCAAGCCCGGCATTTCTAGCTCATATTTCACCGCAGATTGCTCTGA
TTTCTGCTGGACAAAATAACCGCTACAAACATCCTCACCAAGAAACGCTTGAACGTTTCCGAGCACAAAACATGACCATT
TACCGCACAGACCAACAAGGTGCTATCCGCTTTCGAGGCTTAAACCACTGGAAAATTGAGACGGTGAGGTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-696)

• Competence protein (Competence) (213-459)

• Domain of unknown function (DUF4131) (DUF4131) (29-172)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	52.156	99.865	0.521
comEC/celB	Streptococcus mitis NCTC 12261	52.022	99.865	0.52
comEC/celB	Streptococcus pneumoniae TIGR4	51.009	100	0.51
comEC/celB	Streptococcus pneumoniae Rx1	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae D39	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae R6	50.471	100	0.505
comEC	Lactococcus lactis subsp. cremoris KW2	47.114	100	0.472