Detailed information NTG0406161

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GO995_RS03165
• Genome accession: NZ_CP046624
• Coordinates: 593213..595447 (+)
• Length: 744 a.a.
• NCBI ID: WP_202913550.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G3
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 588213..600447

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO995_RS03140 (GO995_03140)	-	588958..590532 (+)	1575	WP_157628821.1	DEAD/DEAH box helicase	-
GO995_RS03145 (GO995_03145)	-	590572..590847 (-)	276	WP_157628822.1	GIY-YIG nuclease family protein	-
GO995_RS03150 (GO995_03150)	-	590822..591583 (-)	762	WP_157628823.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GO995_RS03155 (GO995_03155)	-	591700..592446 (+)	747	WP_074559556.1	lysophospholipid acyltransferase family protein	-
GO995_RS03160 (GO995_03160)	-	592543..593223 (+)	681	WP_157628824.1	helix-hairpin-helix domain-containing protein	-
GO995_RS03165 (GO995_03165)	comEC/celB	593213..595447 (+)	2235	WP_202913550.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GO995_RS03170 (GO995_03170)	holA	595512..596549 (+)	1038	WP_157628826.1	DNA polymerase III subunit delta	-
GO995_RS03175 (GO995_03175)	sodA	596646..597257 (+)	612	WP_039698404.1	superoxide dismutase SodA	-
GO995_RS03180 (GO995_03180)	-	597368..598093 (+)	726	WP_024344280.1	YebC/PmpR family DNA-binding transcriptional regulator	-
GO995_RS03185 (GO995_03185)	queA	598145..599173 (-)	1029	WP_157628827.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
GO995_RS03190 (GO995_03190)	-	599337..599843 (+)	507	WP_033152227.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84221.43 Da
• Isoelectric Point: 8.2166

>NTDB_id=406161 GO995_RS03165 WP_202913550.1 593213..595447(+) (comEC/celB) [Streptococcus ruminicola strain CNU_G3]
MLIKHFPVKPIQLAFLLTLLYYFCFEKVVLCLILLLLALLFLWQQYGWKAWCQVSLCLAFFAIFFLTKSNQTEQAYQAAP
AQLSKIQMVPDTISVNGDLLSFRGKEAGQTYQVFYTLKSEKEQKFFKNLNQTMLLSGQVDLEEATPQRNFGGFDYRTYLK
HEGIYRIANLSSITEMRQQSSLSFFERLHELRRQAIVSIQRNFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVGVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSAFANLGIKKIDNLAFTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYRKILTECLAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLVGTSLVFGRPSLGILLLLLLTIGLLYDCYRRKKVVIFLLSLIALLFFQIKH
PLENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFNQKEGWQERLSDSNADRTLIPYLNSRGVGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVRAVSAGDNLPIMGSHLQVLYPIEVGDGSNNDSVVLYGNLLG
KNFLFTGDLEEEGEREVMAAYPNLPVDVLKAGHHGSKGSSSPEFLEHISPQVALISAGQNNRYKHPHQETLERFQAQNMT
IYRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=406161 GO995_RS03165 WP_202913550.1 593213..595447(+) (comEC/celB) [Streptococcus ruminicola strain CNU_G3]
CTGTTGATTAAGCATTTCCCTGTCAAGCCAATTCAATTGGCTTTTTTGCTCACTTTACTTTATTATTTTTGTTTTGAAAA
AGTGGTGTTATGTCTGATTTTACTCCTGTTAGCCTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAGG
TTTCACTGTGCTTGGCTTTCTTTGCGATATTTTTCCTGACTAAGTCTAATCAGACAGAACAGGCTTATCAAGCGGCGCCA
GCTCAGCTATCAAAAATCCAGATGGTTCCAGATACGATTTCGGTTAATGGTGATTTGTTATCTTTTCGAGGGAAGGAGGC
TGGGCAGACTTACCAAGTTTTTTATACCTTGAAGTCAGAAAAAGAGCAGAAATTTTTTAAAAATCTTAATCAAACAATGC
TTTTATCAGGGCAGGTGGATTTAGAAGAGGCAACGCCACAGCGGAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGCATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATGAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCCCCAATGCAACATTATATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTATACACGAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTTGGCTTTTTTGTTGGTGTTTTTCGCTATTTCTTTTTGCGACTTGGGTTAAGGCGTGATTATGT
GGATATACTCCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTTTCAGTTGTTCGGAGCCTTATTC
AGTCTGCTTTTGCAAATCTTGGCATTAAAAAAATAGATAATCTTGCCTTTACTTTAATGACTCTTTTTATTTTGATGCCA
AATTTCCTGCTGACGACGGGAGGTATTCTTTCGTTTACTTACGCTTTTATCCTGAGTTTTATTGATTTTGATGAGCTTAG
TCATTATCGAAAAATCCTTACAGAATGTTTGGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCCTTGTCGCTGCTTTTAACAGCTATTTTTTCATTGGCATTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACTGCGTTAAATCCATTTTTTGTTTTTCTAGAAACTATCATCAAATTTAGCAA
GTCGCTGGTTGGTACCTCACTCGTTTTTGGCAGACCAAGTCTAGGAATTTTGTTGTTATTACTTTTGACAATAGGGCTTC
TCTATGACTGTTATCGACGTAAAAAAGTGGTCATTTTCCTTCTTAGCTTAATAGCTCTGCTATTTTTCCAAATCAAGCAT
CCGCTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCATACGCT
GTTAATTGATGTCGGAGGAAAAGTGAGTTTTAACCAAAAAGAAGGCTGGCAGGAGCGTTTGTCTGACAGCAATGCAGATC
GAACCTTGATTCCTTATCTCAATAGCCGTGGTGTTGGAAAAATTGACCAGCTGGTTTTGACGCACACGGATACCGATCAT
ATGGGTGATATGCTGGAAGTCGCAAAAGAGCTGAAAATTGGTCAAGTCCTAGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCAGTTCGCGCAGTTTCTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTCTATCCAATTGAAGTTGGTGATGGTTCTAATAATGATTCTGTGGTGCTTTATGGCAATCTTCTAGGT
AAAAATTTTTTGTTTACAGGAGATTTGGAAGAAGAAGGTGAGCGTGAGGTGATGGCGGCTTATCCTAATCTGCCAGTTGA
TGTTTTAAAAGCAGGACACCATGGTTCAAAAGGGTCATCAAGCCCAGAATTTCTAGAGCATATTTCACCGCAAGTTGCTC
TGATTTCCGCAGGACAAAATAACCGCTACAAGCATCCTCATCAAGAAACCCTCGAACGCTTTCAAGCACAAAACATGACC
ATTTACCGTACTGATGAACAAGGTGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (214-458)

• Domain of unknown function (DUF4131) (DUF4131) (29-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	50.943	99.731	0.508
comEC/celB	Streptococcus mitis SK321	50.539	99.731	0.504
comEC/celB	Streptococcus pneumoniae TIGR4	49.798	99.866	0.497
comEC/celB	Streptococcus pneumoniae Rx1	49.26	99.866	0.492
comEC/celB	Streptococcus pneumoniae D39	49.26	99.866	0.492
comEC/celB	Streptococcus pneumoniae R6	49.26	99.866	0.492
comEC	Lactococcus lactis subsp. cremoris KW2	47.664	100	0.48