Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   GOM48_RS07800 Genome accession   NZ_CP046523
Coordinates   1547653..1548390 (-) Length   245 a.a.
NCBI ID   WP_235097047.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1542653..1553390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS07785 (GOM48_07725) - 1544683..1546044 (+) 1362 WP_235097044.1 bacteriocin secretion accessory protein -
  GOM48_RS07790 (GOM48_07730) blpC 1546101..1546256 (+) 156 WP_235097045.1 quorum-sensing system pheromone BlpC -
  GOM48_RS07795 (GOM48_07735) - 1546299..1547639 (-) 1341 WP_235097046.1 sensor histidine kinase -
  GOM48_RS07800 (GOM48_07740) comE/blpR 1547653..1548390 (-) 738 WP_235097047.1 response regulator transcription factor Regulator
  GOM48_RS07805 (GOM48_07745) - 1548395..1548733 (-) 339 WP_235097048.1 LytTR family DNA-binding domain-containing protein -
  GOM48_RS07810 (GOM48_07750) - 1549013..1549342 (+) 330 WP_235097049.1 helicase BlpT -
  GOM48_RS07815 (GOM48_07755) - 1549511..1550560 (-) 1050 WP_235097050.1 ABC transporter permease -
  GOM48_RS07820 (GOM48_07760) pptA 1550557..1551288 (-) 732 WP_235097051.1 ABC transporter ATP-binding protein Regulator
  GOM48_RS07825 (GOM48_07765) - 1551356..1551766 (+) 411 WP_235097052.1 HIT family protein -
  GOM48_RS07830 (GOM48_07770) - 1551776..1552054 (+) 279 WP_235097053.1 hypothetical protein -
  GOM48_RS07835 (GOM48_07775) - 1552118..1552777 (+) 660 WP_235097054.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28780.03 Da        Isoelectric Point: 6.6107

>NTDB_id=404932 GOM48_RS07800 WP_235097047.1 1547653..1548390(-) (comE/blpR) [Streptococcus oralis strain SOD]
MRIFVLEDDFSQQARIETTIEKLLKKHYITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSVEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPTNVARLDKKEKLLFFPNGGSCLIARYKVREVSEA
ITNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=404932 GOM48_RS07800 WP_235097047.1 1547653..1548390(-) (comE/blpR) [Streptococcus oralis strain SOD]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAAGCTAGGATTGAAACGACGATTGAGAAACTCTTGAAGAAACA
TTATATCACTCCCAGCTCTTTTGAAGTCTTTGGCAAGCCAGATCAACTGCTGGCAGAGGTGCATGAGAAGGGAGCACATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAAGAAATGAAAGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTGATAGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTCTCCTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCCTTTCGGTAGAGGAGTTTGAATCTCGGATTGAGACAGCCCTTCTCTATGCCAATGGTCAAGATA
GTAAAAGCCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTTAAGGAGGTTTACTAT
CTCGAAACGTCACCCAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACGGCGAGTTTAGAGGA
GGTTCTCAAGCAGGAACCCCGTCTCTTGCAGTGCCACCGCTCCTTTCTCATCAATCCAACCAATGTAGCTCGTTTGGATA
AAAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATCACTAACTTGCACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.535
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment