Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GE024_RS05710 Genome accession   NZ_CP046521
Coordinates   1123062..1124372 (-) Length   436 a.a.
NCBI ID   WP_093998603.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1118062..1129372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS05680 (GE024_05690) - 1118210..1118599 (-) 390 WP_003048314.1 cytidine deaminase -
  GE024_RS05685 (GE024_05695) deoC 1118586..1119248 (-) 663 WP_003048312.1 deoxyribose-phosphate aldolase -
  GE024_RS05690 (GE024_05700) - 1119264..1120541 (-) 1278 WP_093998605.1 pyrimidine-nucleoside phosphorylase -
  GE024_RS05695 (GE024_05705) - 1120528..1121127 (-) 600 WP_003048308.1 class I SAM-dependent methyltransferase -
  GE024_RS05700 (GE024_05710) coaA 1121395..1122315 (+) 921 WP_093998604.1 type I pantothenate kinase -
  GE024_RS05705 (GE024_05715) rpsT 1122369..1122617 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  GE024_RS05710 (GE024_05720) ciaH 1123062..1124372 (-) 1311 WP_093998603.1 cell wall metabolism sensor histidine kinase WalK Regulator
  GE024_RS05715 (GE024_05725) ciaR 1124365..1125039 (-) 675 WP_003048303.1 response regulator transcription factor Regulator
  GE024_RS05720 (GE024_05730) - 1125242..1127779 (-) 2538 WP_093998602.1 M1 family metallopeptidase -
  GE024_RS05725 (GE024_05735) phoU 1127985..1128638 (-) 654 WP_003048299.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49748.32 Da        Isoelectric Point: 9.4415

>NTDB_id=404860 GE024_RS05710 WP_093998603.1 1123062..1124372(-) (ciaH) [Streptococcus canis strain HL_100]
MSKLKKEILSDQYTHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNII
KALPDSDSSKLLGSPAANTDIILFSANGTILNSFNAFSNYQNFHLDERRLGTIVTTSLVNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVDQLDSANERYEQIIIIVMVIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDAQFFDTIFKNYQLVVEESGKVFRSDN
QVNRILKMDKALLKQLMTILVDNAIKYTDKNGVVEIKVKTTDKTLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVTSLKGSITVKDNFPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=404860 GE024_RS05710 WP_093998603.1 1123062..1124372(-) (ciaH) [Streptococcus canis strain HL_100]
ATGAGTAAATTAAAAAAAGAGATTCTGTCAGATCAGTACACTCACTTTTTCCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTCATTATGACCATTATTATTTTACAGATTATGAGGTTTGGGGTTTATTCGTCTGTTGATAGTAGCCTGATTTCTGTTA
GTAATAATGCTAGTAGTTATGCCAATCGAACCATGGCTAGAATATCCTCCTTCTACTTTGATGCTGAAAATAATATTATT
AAGGCGCTACCTGACTCTGATAGTTCAAAATTACTAGGCTCCCCTGCAGCTAATACAGATATTATTTTGTTCAGTGCTAA
TGGGACGATTTTAAATTCCTTCAATGCCTTCTCCAATTACCAAAATTTTCATCTGGACGAACGACGGTTAGGAACCATTG
TGACAACTAGTCTCGTGAATTTTTATGGTCAAGAAGAAAAGTACCATACGATAACTGTTAGGGTCCATATCAAAAATTAC
CCTGCTGTCGCTTATATGATGGCTGTTGTCAATGTGGATCAATTGGATAGCGCTAATGAACGCTATGAGCAAATCATCAT
CATTGTGATGGTTATCTTTTGGCTGATTTCCATTTTAGCTAGTATTTATTTATCTAAGTGGAGTCGAAAACCGATTTTGG
AAAGTTATGAAAAGCAAAAGATGTTTGTGGAAAATGCCAGCCATGAATTAAGAACCCCTCTAGCTGTTTTACAAAACCGC
TTGGAATCCCTCTTTCGAAAACCTAACGAAACTATTTTGGAAAATAGTGAGCACCTTGCCTCTAGTTTGGACGAAGTTCG
AAACATGCGTATTCTAACGACCAATCTATTGAATTTGGCCAGGCGAGATGACGGTATCAATCCGCAATGGACAGATTTGG
ATGCTCAATTCTTTGATACCATTTTTAAGAACTATCAATTAGTTGTTGAAGAATCTGGCAAAGTCTTTCGCTCCGATAAT
CAAGTCAATCGCATCTTGAAAATGGACAAGGCATTATTAAAACAACTCATGACGATTTTAGTCGATAATGCCATCAAATA
CACCGATAAAAATGGAGTAGTTGAGATAAAGGTCAAAACAACCGATAAAACCTTGCTCATTTCGGTTATTGATAATGGGC
CAGGGATAAAAGACGAAGAGAAGAAAAAGATTTTTGATCGATTCTATCGGGTTGATAAAGCTAGAACACGCCAGACAGGT
GGCTTTGGCTTAGGATTAGCATTAGCCCAACAGATTGTGACGTCATTAAAAGGAAGTATCACAGTAAAAGATAACTTCCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

50.913

100

0.511
  ciaH Streptococcus pneumoniae D39

50.913

100

0.511
  ciaH Streptococcus pneumoniae R6

50.913

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

50.913

100

0.511

Multiple sequence alignment