Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SPYALAB49_RS08695 Genome accession   NC_017596
Coordinates   1749183..1749950 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes Alab49     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1744183..1754950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS08685 (SPYALAB49_001787) hexB 1744692..1746674 (-) 1983 WP_002992189.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPYALAB49_RS08690 (SPYALAB49_001788) - 1746769..1747920 (-) 1152 WP_014635780.1 site-specific integrase -
  SPYALAB49_RS10070 (SPYALAB49_001789) - 1748169..1748312 (+) 144 WP_011185066.1 putative holin-like toxin -
  SPYALAB49_RS08695 (SPYALAB49_001790) irvR 1749183..1749950 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  SPYALAB49_RS08700 (SPYALAB49_001791) - 1750104..1750310 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  SPYALAB49_RS08705 (SPYALAB49_001792) - 1750344..1751111 (+) 768 WP_010922759.1 Bro-N domain-containing protein -
  SPYALAB49_RS08710 (SPYALAB49_001793) - 1751121..1751744 (+) 624 WP_010922760.1 phage repressor protein -
  SPYALAB49_RS08715 (SPYALAB49_001794) - 1751771..1752013 (+) 243 WP_014635782.1 hypothetical protein -
  SPYALAB49_RS08725 (SPYALAB49_001795) - 1752271..1753404 (-) 1134 WP_000564846.1 ISAs1-like element IS1548 family transposase -
  SPYALAB49_RS08730 (SPYALAB49_001796) - 1753595..1753936 (+) 342 WP_010922762.1 hypothetical protein -
  SPYALAB49_RS08735 (SPYALAB49_001797) - 1753923..1754144 (+) 222 WP_014635783.1 hypothetical protein -
  SPYALAB49_RS08740 (SPYALAB49_001798) - 1754147..1754338 (+) 192 WP_010922764.1 hypothetical protein -
  SPYALAB49_RS08745 (SPYALAB49_001799) - 1754350..1754679 (+) 330 WP_003058810.1 hypothetical protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=40444 SPYALAB49_RS08695 WP_003058809.1 1749183..1749950(-) (irvR) [Streptococcus pyogenes Alab49]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=40444 SPYALAB49_RS08695 WP_003058809.1 1749183..1749950(-) (irvR) [Streptococcus pyogenes Alab49]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4

Multiple sequence alignment