Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   SPYALAB49_RS05540 Genome accession   NC_017596
Coordinates   1100644..1101606 (-) Length   320 a.a.
NCBI ID   WP_002983995.1    Uniprot ID   -
Organism   Streptococcus pyogenes Alab49     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1095644..1106606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS05525 (SPYALAB49_001133) - 1096481..1097188 (-) 708 WP_011284934.1 O-methyltransferase -
  SPYALAB49_RS05530 (SPYALAB49_001134) - 1097254..1098450 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  SPYALAB49_RS05535 (SPYALAB49_001135) pepF 1098826..1100631 (-) 1806 WP_011054652.1 oligoendopeptidase F Regulator
  SPYALAB49_RS05540 (SPYALAB49_001136) coiA 1100644..1101606 (-) 963 WP_002983995.1 competence protein CoiA Machinery gene
  SPYALAB49_RS05545 (SPYALAB49_001137) - 1101901..1102617 (-) 717 WP_002995774.1 pseudouridine synthase -
  SPYALAB49_RS05550 (SPYALAB49_001138) nagB 1102736..1103440 (-) 705 WP_009880651.1 glucosamine-6-phosphate deaminase -
  SPYALAB49_RS05555 (SPYALAB49_001139) queA 1103642..1104670 (+) 1029 WP_002995782.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  SPYALAB49_RS05560 (SPYALAB49_001140) - 1104677..1105897 (+) 1221 WP_002983986.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37801.25 Da        Isoelectric Point: 10.2848

>NTDB_id=40406 SPYALAB49_RS05540 WP_002983995.1 1100644..1101606(-) (coiA) [Streptococcus pyogenes Alab49]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=40406 SPYALAB49_RS05540 WP_002983995.1 1100644..1101606(-) (coiA) [Streptococcus pyogenes Alab49]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403

Multiple sequence alignment