Detailed information NTG0403677

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GL187_RS04545
• Genome accession: NZ_CP046379
• Coordinates: 892471..893424 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain 563
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 887471..898424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS04520 (GL187_04605)	rpmG	888214..888363 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
GL187_RS04525 (GL187_04610)	secG	888403..888636 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
GL187_RS04530 (GL187_04615)	rnr	888738..891092 (+)	2355	WP_024477774.1	ribonuclease R	-
GL187_RS04535 (GL187_04620)	smpB	891055..891522 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
GL187_RS04540 (GL187_04625)	tehB	891538..892398 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
GL187_RS04545 (GL187_04630)	coiA	892471..893424 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
GL187_RS04550 (GL187_04635)	pepF	893443..895245 (+)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
GL187_RS04555 (GL187_04640)	-	895247..895960 (+)	714	WP_000230399.1	O-methyltransferase	-
GL187_RS04560 (GL187_04645)	prsA	896027..896968 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
GL187_RS04565 (GL187_04650)	-	897087..897428 (-)	342	Protein_911	transposase	-
GL187_RS04570 (GL187_04655)	-	897840..897935 (+)	96	Protein_912	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=403677 GL187_RS04545 WP_000495911.1 892471..893424(+) (coiA) [Streptococcus pneumoniae strain 563]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=403677 GL187_RS04545 WP_000495911.1 892471..893424(+) (coiA) [Streptococcus pneumoniae strain 563]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435