Detailed information NTG0403364

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: GL188_RS09770
• Genome accession: NZ_CP046359
• Coordinates: 1910546..1911007 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 573
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1905546..1916007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL188_RS09740 (GL188_09900)	-	1905859..1906683 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
GL188_RS09745 (GL188_09905)	rnpA	1906658..1907029 (-)	372	WP_000739247.1	ribonuclease P protein component	-
GL188_RS11310	-	1907046..1907177 (-)	132	WP_000768904.1	hypothetical protein	-
GL188_RS09750 (GL188_09910)	-	1907178..1908368 (-)	1191	WP_000167765.1	acetate kinase	-
GL188_RS09755 (GL188_09915)	comYH	1908419..1909372 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
GL188_RS09760 (GL188_09920)	-	1909433..1910020 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
GL188_RS09765 (GL188_09925)	comGG/cglG	1910176..1910568 (-)	393	WP_001818028.1	competence type IV pilus minor pilin ComGG	Machinery gene
GL188_RS09770 (GL188_09930)	comGF/cglF	1910546..1911007 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
GL188_RS09775 (GL188_09935)	comGE/cglE	1910970..1911272 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GL188_RS09780 (GL188_09940)	comGD/cglD	1911235..1911639 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
GL188_RS09785 (GL188_09945)	comGC/cglC	1911632..1911958 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
GL188_RS09790 (GL188_09950)	comGB/cglB	1911960..1912976 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
GL188_RS09795 (GL188_09955)	comGA/cglA/cilD	1912924..1913865 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
GL188_RS09800 (GL188_09960)	-	1913940..1914305 (-)	366	WP_000286415.1	DUF1033 family protein	-
GL188_RS09805 (GL188_09965)	-	1914456..1915514 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=403364 GL188_RS09770 WP_000250539.1 1910546..1911007(-) (comGF/cglF) [Streptococcus pneumoniae strain 573]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=403364 GL188_RS09770 WP_000250539.1 1910546..1911007(-) (comGF/cglF) [Streptococcus pneumoniae strain 573]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915