Detailed information NTG0403158

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GL185_RS03005
• Genome accession: NZ_CP046357
• Coordinates: 604828..605781 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain 525
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 599828..610781

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL185_RS02980 (GL185_03010)	-	600317..600412 (-)	96	Protein_596	IS630 family transposase	-
GL185_RS02985 (GL185_03015)	-	600824..601165 (+)	342	Protein_597	IS3 family transposase	-
GL185_RS02990 (GL185_03020)	prsA	601284..602225 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
GL185_RS02995 (GL185_03025)	-	602292..603005 (-)	714	WP_000230399.1	O-methyltransferase	-
GL185_RS03000 (GL185_03030)	pepF	603007..604809 (-)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
GL185_RS03005 (GL185_03035)	coiA	604828..605781 (-)	954	WP_000495911.1	competence protein CoiA	Machinery gene
GL185_RS03010 (GL185_03040)	tehB	605854..606714 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
GL185_RS03015 (GL185_03045)	smpB	606730..607197 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
GL185_RS03020 (GL185_03050)	rnr	607160..609514 (-)	2355	WP_024477774.1	ribonuclease R	-
GL185_RS03025 (GL185_03055)	secG	609616..609849 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
GL185_RS03030 (GL185_03060)	rpmG	609889..610038 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=403158 GL185_RS03005 WP_000495911.1 604828..605781(-) (coiA) [Streptococcus pneumoniae strain 525]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=403158 GL185_RS03005 WP_000495911.1 604828..605781(-) (coiA) [Streptococcus pneumoniae strain 525]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435