Detailed information NTG0403049

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GL183_RS06690
• Genome accession: NZ_CP046355
• Coordinates: 1285965..1286918 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain 475
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1280965..1291918

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL183_RS06665 (GL183_06715)	-	1281454..1281549 (-)	96	Protein_1278	IS630 family transposase	-
GL183_RS06670 (GL183_06720)	-	1281961..1282302 (+)	342	Protein_1279	IS3 family transposase	-
GL183_RS06675 (GL183_06725)	prsA	1282421..1283362 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
GL183_RS06680 (GL183_06730)	-	1283429..1284142 (-)	714	WP_000230399.1	O-methyltransferase	-
GL183_RS06685 (GL183_06735)	pepF	1284144..1285946 (-)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
GL183_RS06690 (GL183_06740)	coiA	1285965..1286918 (-)	954	WP_000495911.1	competence protein CoiA	Machinery gene
GL183_RS06695 (GL183_06745)	tehB	1286991..1287851 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
GL183_RS06700 (GL183_06750)	smpB	1287867..1288334 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
GL183_RS06705 (GL183_06755)	rnr	1288297..1290651 (-)	2355	WP_024477774.1	ribonuclease R	-
GL183_RS06710 (GL183_06760)	secG	1290753..1290986 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
GL183_RS06715 (GL183_06765)	rpmG	1291026..1291175 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=403049 GL183_RS06690 WP_000495911.1 1285965..1286918(-) (coiA) [Streptococcus pneumoniae strain 475]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=403049 GL183_RS06690 WP_000495911.1 1285965..1286918(-) (coiA) [Streptococcus pneumoniae strain 475]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435