Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   GLO74_RS10750 Genome accession   NZ_CP046354
Coordinates   2097296..2097532 (-) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 310     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2097849..2099476 2097296..2097532 flank 317


Gene organization within MGE regions


Location: 2097296..2099476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS10750 (GLO74_10955) comW 2097296..2097532 (-) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  GLO74_RS10755 (GLO74_10960) - 2097798..2098595 (+) 798 Protein_2099 transposase -
  GLO74_RS10760 (GLO74_10965) - 2098630..2099476 (-) 847 Protein_2100 IS630 family transposase -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=402990 GLO74_RS10750 WP_000939544.1 2097296..2097532(-) (comW) [Streptococcus pneumoniae strain 310]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=402990 GLO74_RS10750 WP_000939544.1 2097296..2097532(-) (comW) [Streptococcus pneumoniae strain 310]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769

Multiple sequence alignment