Detailed information NTG0402968

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: GLO74_RS06405
• Genome accession: NZ_CP046354
• Coordinates: 1239240..1240193 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain 310
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1234240..1245193

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLO74_RS06380 (GLO74_06465)	-	1234729..1234824 (-)	96	Protein_1218	IS630 family transposase	-
GLO74_RS06385 (GLO74_06470)	-	1235236..1235577 (+)	342	Protein_1219	transposase	-
GLO74_RS06390 (GLO74_06475)	prsA	1235696..1236637 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
GLO74_RS06395 (GLO74_06480)	-	1236704..1237417 (-)	714	WP_000230399.1	O-methyltransferase	-
GLO74_RS06400 (GLO74_06485)	pepF	1237419..1239221 (-)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
GLO74_RS06405 (GLO74_06490)	coiA	1239240..1240193 (-)	954	WP_000495911.1	competence protein CoiA	Machinery gene
GLO74_RS06410 (GLO74_06495)	tehB	1240266..1241126 (-)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
GLO74_RS06415 (GLO74_06500)	smpB	1241142..1241609 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
GLO74_RS06420 (GLO74_06505)	rnr	1241572..1243926 (-)	2355	WP_024477774.1	ribonuclease R	-
GLO74_RS06425 (GLO74_06510)	secG	1244028..1244261 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
GLO74_RS06430 (GLO74_06515)	rpmG	1244301..1244450 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=402968 GLO74_RS06405 WP_000495911.1 1239240..1240193(-) (coiA) [Streptococcus pneumoniae strain 310]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=402968 GLO74_RS06405 WP_000495911.1 1239240..1240193(-) (coiA) [Streptococcus pneumoniae strain 310]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435