Detailed information NTG0402938

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GLO74_RS01330
• Genome accession: NZ_CP046354
• Coordinates: 253531..254541 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 310
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 248531..259541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLO74_RS01300 (GLO74_01330)	-	249401..249607 (+)	207	WP_000503437.1	hypothetical protein	-
GLO74_RS01305 (GLO74_01335)	-	249604..249798 (+)	195	WP_000820180.1	hypothetical protein	-
GLO74_RS01310 (GLO74_01340)	-	249785..250669 (+)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GLO74_RS01315 (GLO74_01345)	-	250671..251408 (+)	738	WP_000832834.1	ABC transporter permease	-
GLO74_RS01320 (GLO74_01350)	-	251408..252505 (+)	1098	WP_000893546.1	sensor histidine kinase	-
GLO74_RS01325 (GLO74_01355)	-	252507..253106 (+)	600	WP_000866719.1	response regulator transcription factor	-
GLO74_RS01330 (GLO74_01360)	ccpA	253531..254541 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
GLO74_RS01335 (GLO74_01365)	-	254747..255709 (-)	963	WP_001124777.1	asparaginase	-
GLO74_RS01340 (GLO74_01370)	-	255775..257163 (+)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GLO74_RS01345 (GLO74_01375)	-	257198..257650 (-)	453	WP_000079148.1	universal stress protein	-
GLO74_RS01350 (GLO74_01380)	-	257813..258106 (+)	294	WP_000977366.1	hypothetical protein	-
GLO74_RS01355 (GLO74_01385)	-	258262..259476 (+)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=402938 GLO74_RS01330 WP_000990607.1 253531..254541(+) (ccpA) [Streptococcus pneumoniae strain 310]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=402938 GLO74_RS01330 WP_000990607.1 253531..254541(+) (ccpA) [Streptococcus pneumoniae strain 310]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568