Detailed information NTG0402808

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: FOB92_RS04140
• Genome accession: NZ_CP046335
• Coordinates: 803543..804496 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495920.1
• Uniprot ID: A0A081SCJ1
• Organism: Streptococcus mitis strain FDAARGOS_684
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 798543..809496

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB92_RS04115 (FOB92_04115)	rpmG	799287..799436 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
FOB92_RS04120 (FOB92_04120)	secG	799476..799709 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
FOB92_RS04125 (FOB92_04125)	rnr	799811..802165 (+)	2355	WP_000654876.1	ribonuclease R	-
FOB92_RS04130 (FOB92_04130)	smpB	802128..802595 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
FOB92_RS04135 (FOB92_04135)	tehB	802610..803470 (+)	861	WP_000413782.1	SAM-dependent methyltransferase TehB	-
FOB92_RS04140 (FOB92_04140)	coiA	803543..804496 (+)	954	WP_000495920.1	competence protein CoiA	Machinery gene
FOB92_RS04145 (FOB92_04145)	pepF	804515..806317 (+)	1803	WP_000244089.1	oligoendopeptidase F	Regulator
FOB92_RS04150 (FOB92_04150)	-	806319..807032 (+)	714	WP_004239376.1	O-methyltransferase	-
FOB92_RS04155 (FOB92_04155)	prsA	807099..808037 (+)	939	WP_000727954.1	peptidylprolyl isomerase PrsA	-
FOB92_RS04160 (FOB92_04160)	ftsW	808198..809421 (+)	1224	WP_000703370.1	cell division peptidoglycan polymerase FtsW	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38161.88 Da
• Isoelectric Point: 8.3929

>NTDB_id=402808 FOB92_RS04140 WP_000495920.1 803543..804496(+) (coiA) [Streptococcus mitis strain FDAARGOS_684]
MFVARDSRGELVNVLEDKLEKQAYTCPACGGQLRLRQGPSVRIHFAHKTLKDCDFSSENESPEHLENKEVLYHWLKKEAE
VQLEYLLPELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGKKLWLKERLTRLQQGFLYFSQNMGF
YVWELDSEKQVLRLKYLIHQDLRGKLHYQIKEFPYGHGSLLEILRFPYKKQKISHFTVSQDKDICRYIRQQLYYQNPIWM
KEQAEAYKKGENLLTYGLKEWYPQIRPLVGNFCQIEQDLIRYYLYFQTYYQENPQNDWQMLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=402808 FOB92_RS04140 WP_000495920.1 803543..804496(+) (coiA) [Streptococcus mitis strain FDAARGOS_684]
ATGTTTGTTGCGAGAGATTCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAGCTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGTCAGCTCCGTTTGCGTCAAGGACCAAGTGTCCGGATCCATTTTGCCCACAAAACCTTAAAAGACTGTG
ATTTTTCCTCTGAAAATGAAAGTCCAGAACATCTGGAAAATAAGGAAGTCCTTTATCACTGGTTGAAAAAAGAGGCCGAG
GTGCAATTAGAATACCTGCTTCCAGAGCTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTTTAGAGGTTCA
ATGTAGTCCCTTGCCTCAAAAAGTTCTTAAAGAGCGTAGCGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGAAAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAACAAGGTTTTCTCTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAGTGAAAAACAAGTTTTAAGACTCAAATACCTGATTCACCAAGATCTCCGAGGTAAACTCCA
TTATCAGATTAAGGAATTTCCCTATGGTCACGGTAGTTTACTGGAGATATTACGTTTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTCAGGACAAGGACATCTGTCGTTATATCCGGCAACAACTGTACTATCAAAATCCCATTTGGATG
AAAGAACAAGCAGAAGCCTATAAAAAGGGAGAAAATCTCCTGACTTATGGGCTAAAAGAATGGTATCCACAAATTCGACC
ACTAGTAGGTAATTTTTGCCAAATTGAGCAAGATTTGATTCGCTATTATCTGTATTTTCAAACCTATTATCAAGAAAATC
CTCAAAATGATTGGCAAATGCTCTATCCACCAGCCTTTTATCAGCAATATTTCTTAAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-256)

3D structure

• AlphaFold DB: A0A081SCJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	100	100	1
coiA	Streptococcus pneumoniae TIGR4	89.274	100	0.893
coiA	Streptococcus pneumoniae Rx1	89.274	100	0.893
coiA	Streptococcus pneumoniae D39	89.274	100	0.893
coiA	Streptococcus pneumoniae R6	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	44.099	100	0.448