Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SOR_RS05830 Genome accession   NC_015291
Coordinates   1168078..1169415 (-) Length   445 a.a.
NCBI ID   WP_013670240.1    Uniprot ID   F2QDY3
Organism   Streptococcus oralis Uo5     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1163078..1174415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS05805 (SOR_1189) rpiA 1163751..1164434 (-) 684 WP_000429270.1 ribose-5-phosphate isomerase RpiA -
  SOR_RS05810 (SOR_1190) - 1164540..1165469 (-) 930 WP_000411175.1 peptidase U32 family protein -
  SOR_RS05815 (SOR_1191) - 1165595..1166275 (-) 681 WP_000209233.1 ABC transporter ATP-binding protein -
  SOR_RS05820 (SOR_1192) - 1166289..1167344 (-) 1056 WP_000280276.1 ABC transporter permease -
  SOR_RS05825 (SOR_1193) - 1167729..1168013 (+) 285 WP_001276163.1 DUF3270 domain-containing protein -
  SOR_RS05830 (SOR_1194) ciaH 1168078..1169415 (-) 1338 WP_013670240.1 sensor histidine kinase Regulator
  SOR_RS05835 (SOR_1195) ciaR 1169405..1170079 (-) 675 WP_000590641.1 two-component system response regulator CiaR Regulator
  SOR_RS05840 (SOR_1196) - 1170189..1172735 (-) 2547 WP_001149134.1 M1 family metallopeptidase -
  SOR_RS05845 (SOR_1197) - 1172856..1173296 (-) 441 WP_013670241.1 ASCH domain-containing protein -
  SOR_RS05850 (SOR_1198) - 1173238..1174140 (-) 903 WP_001245873.1 putative PEP-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 50922.71 Da        Isoelectric Point: 9.7098

>NTDB_id=40201 SOR_RS05830 WP_013670240.1 1168078..1169415(-) (ciaH) [Streptococcus oralis Uo5]
MFNKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDEKLQALSSSPQAVIQLALNRATEEVKDIQPAT
ADASKAEIKPNVSSNTEVLLFDKDFNQLLLGNRFLGLDKIKLDKKELNHIRQIQVVNSYGLEETYRIVLMETNSSTVSSN
VKYAAVLINTSQLEQISQKHEHLIVVVMASFWLLSLIASVYLARVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLE
NLFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEIAEVSPQFFKTTFANYELIAYENDRFFNYENRI
YRPFMTDQLLLKQLMTILFDNAIKYTEEDGKIEFVVYATDRHLYLTVTDNGIGISAADKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALRGTISVKDNKPRGTIFEVKIAIQSPSKRKNK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=40201 SOR_RS05830 WP_013670240.1 1168078..1169415(-) (ciaH) [Streptococcus oralis Uo5]
ATGTTCAATAAACTAAAAAAAACATGGTATGCAGATGATTTCAGCTATTTCATTCGAAACTTTGGAGTGTTCACACTGAT
TTTCTCTACTATGACCTTGATTATCCTACAGGTCATGCACTCCAGTCTCTATACTTCTGTAGATGAAAAACTACAAGCCC
TTAGTAGTAGTCCTCAAGCGGTCATTCAGTTAGCCCTGAATCGGGCAACTGAGGAAGTCAAAGATATTCAACCCGCAACT
GCGGATGCCAGCAAGGCTGAAATCAAGCCCAATGTTAGCTCCAATACAGAAGTTTTGCTTTTTGACAAGGATTTTAACCA
ACTCTTACTGGGTAATCGCTTTTTAGGCTTGGACAAGATCAAGCTGGACAAGAAAGAGTTGAATCATATTCGGCAAATCC
AAGTTGTCAACAGCTATGGTCTGGAAGAAACCTATCGAATTGTCTTGATGGAAACCAACTCTTCCACCGTATCAAGTAAT
GTCAAATATGCGGCGGTTCTAATCAATACCAGCCAGCTTGAGCAAATCAGCCAAAAACACGAGCATTTAATTGTTGTAGT
GATGGCTAGTTTCTGGCTCCTCTCTTTAATTGCCAGTGTTTACCTGGCACGTGTCAGTGTCAAACCGCTACTGGAAAGCA
TGCAAAAGCAGAAGTCTTTTGTTGAAAATGCGAGTCATGAACTGAGAACGCCTTTGGCCGTTTTACAAAATCGTTTAGAG
AATCTCTTTCGAAAACCAGAGGCAACAATCATGGAATCCAGCGAAAGTATCGCTTCCAGTCTTGAAGAGGTTCGCAATAT
GCGTTTCCTCACGACCAATCTTCTCAACCTTGCACGTCGAGATGATGGAATCAAACCAGAAATAGCAGAAGTTTCTCCAC
AATTCTTTAAAACAACCTTTGCCAACTATGAGTTGATTGCTTATGAAAATGATCGTTTTTTCAACTATGAAAATCGAATT
TATCGTCCATTCATGACCGATCAGTTGCTCTTAAAACAACTCATGACTATCTTGTTTGACAATGCCATCAAGTATACCGA
AGAAGATGGCAAGATTGAGTTTGTAGTCTATGCTACAGATCGCCACCTCTATCTTACAGTAACGGATAACGGAATTGGAA
TTTCAGCTGCTGACAAGAAGAAAATCTTTGACCGCTTTTACCGTGTGGACAAGGCGAGAACCCGTCAGAAAGGTGGCTTT
GGTCTTGGACTATCTTTGGCCAAGCAGATCGTAGATGCCTTACGAGGAACGATTAGCGTAAAAGATAACAAACCTAGAGG
AACAATTTTTGAAGTTAAGATCGCTATTCAATCTCCTTCAAAACGTAAGAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QDY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae D39

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae R6

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae TIGR4

83.747

99.551

0.834
  ciaH Streptococcus mutans UA159

55.023

98.427

0.542

Multiple sequence alignment