Detailed information NTG0040187

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: SOR_RS02360
• Genome accession: NC_015291
• Coordinates: 453368..454027 (-)
• Length: 219 a.a.
• NCBI ID: WP_000566521.1
• Uniprot ID: F2QBX6
• Organism: Streptococcus oralis Uo5
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 448368..459027

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOR_RS02330 (SOR_0474)	-	448495..449061 (+)	567	WP_000601895.1	aminodeoxychorismate/anthranilate synthase component II	-
SOR_RS02335 (SOR_0475)	trpD	449072..450076 (+)	1005	WP_000658690.1	anthranilate phosphoribosyltransferase	-
SOR_RS02340 (SOR_0476)	trpC	450073..450840 (+)	768	WP_000076521.1	indole-3-glycerol phosphate synthase TrpC	-
SOR_RS02345 (SOR_0477)	-	450827..451426 (+)	600	WP_000169867.1	phosphoribosylanthranilate isomerase	-
SOR_RS02350 (SOR_0478)	trpB	451404..452627 (+)	1224	WP_000331269.1	tryptophan synthase subunit beta	-
SOR_RS02355 (SOR_0479)	trpA	452620..453396 (+)	777	WP_001127035.1	tryptophan synthase subunit alpha	-
SOR_RS02360 (SOR_0480)	cclA/cilC	453368..454027 (-)	660	WP_000566521.1	prepilin peptidase	Machinery gene
SOR_RS02365 (SOR_0481)	-	454097..454552 (+)	456	WP_000973466.1	GNAT family N-acetyltransferase	-
SOR_RS02370 (SOR_0482)	-	454656..455180 (+)	525	WP_000089607.1	hypothetical protein	-
SOR_RS02375 (SOR_0483)	-	455250..455771 (+)	522	WP_000493728.1	hypothetical protein	-
SOR_RS02380 (SOR_0484)	-	455991..456194 (-)	204	WP_000102421.1	CsbD family protein	-
SOR_RS02385 (SOR_0485)	-	456236..456820 (-)	585	WP_000072933.1	Asp23/Gls24 family envelope stress response protein	-
SOR_RS02390 (SOR_0486)	-	456832..457002 (-)	171	WP_000454669.1	DUF2273 domain-containing protein	-
SOR_RS02395 (SOR_0487)	amaP	457013..457576 (-)	564	WP_000045617.1	alkaline shock response membrane anchor protein AmaP	-
SOR_RS02400 (SOR_0488)	-	457676..457912 (-)	237	WP_000964740.1	GlsB/YeaQ/YmgE family stress response membrane protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24900.01 Da
• Isoelectric Point: 7.8974

>NTDB_id=40187 SOR_RS02360 WP_000566521.1 453368..454027(-) (cclA/cilC) [Streptococcus oralis Uo5]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPSDLIPILSQVFNRFRCRYCKIRYPVWYALFELGLG
LLFLAWSWGWISLGQVILITAGLTLGIYDLRHQEYPLLVWLTFHLILMACTSWNLDMVFFLALGILAHFIDIRMGAGDFL
FLASCALIFSATELLILIQFASAAGILAFLLQKKKERLPFVPFLLLAACLIIFGNLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=40187 SOR_RS02360 WP_000566521.1 453368..454027(-) (cclA/cilC) [Streptococcus oralis Uo5]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTAGGTTTGGTCATTGACCGTTTTCCTGAGCA
ATCCATTATTCGACCAGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTCAGATTTGATTCCTATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGATTCGCTATCCTGTTTGGTATGCCCTCTTTGAACTCGGCTTAGGA
CTCCTCTTTCTAGCTTGGTCATGGGGCTGGATTTCCTTGGGGCAAGTCATCCTCATAACTGCTGGCTTGACCTTAGGTAT
CTACGACCTTCGTCATCAGGAATATCCCTTACTAGTCTGGCTGACGTTCCACCTAATCCTCATGGCCTGTACTAGTTGGA
ATCTGGATATGGTCTTCTTTCTTGCCCTTGGAATTTTAGCTCATTTTATCGATATCCGCATGGGAGCAGGGGATTTTCTA
TTTCTGGCTTCTTGTGCTCTCATCTTTAGCGCGACAGAATTACTCATCTTGATTCAGTTCGCTTCTGCGGCAGGCATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTTTGATTATTTTTG
GTAATCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

3D structure

• AlphaFold DB: F2QBX6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	89.954	100	0.9
cclA/cilC	Streptococcus pneumoniae Rx1	88.128	100	0.881
cclA/cilC	Streptococcus pneumoniae D39	88.128	100	0.881
cclA/cilC	Streptococcus pneumoniae R6	88.128	100	0.881
cclA/cilC	Streptococcus pneumoniae TIGR4	87.671	100	0.877
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872