Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   SGGBAA2069_RS10025 Genome accession   NC_015215
Coordinates   2015734..2017098 (-) Length   454 a.a.
NCBI ID   WP_039695025.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2010734..2022098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS09990 (SGGBAA2069_c19570) rmuC 2010826..2012100 (-) 1275 WP_013643474.1 DNA recombination protein RmuC -
  SGGBAA2069_RS09995 (SGGBAA2069_c19580) - 2012102..2012731 (-) 630 WP_013643475.1 thiamine diphosphokinase -
  SGGBAA2069_RS10000 (SGGBAA2069_c19590) rpe 2012724..2013386 (-) 663 WP_013643476.1 ribulose-phosphate 3-epimerase -
  SGGBAA2069_RS10005 (SGGBAA2069_c19600) rsgA 2013393..2014265 (-) 873 WP_013643477.1 ribosome small subunit-dependent GTPase A -
  SGGBAA2069_RS10020 (SGGBAA2069_c19610) - 2015402..2015602 (-) 201 WP_013643478.1 hypothetical protein -
  SGGBAA2069_RS10025 (SGGBAA2069_c19620) comD/comD3 2015734..2017098 (-) 1365 WP_039695025.1 GHKL domain-containing protein Regulator
  SGGBAA2069_RS10030 (SGGBAA2069_c19630) comE/comE2 2017111..2017839 (-) 729 WP_043913786.1 LytR/AlgR family response regulator transcription factor Regulator
  SGGBAA2069_RS10035 (SGGBAA2069_c19640) - 2017937..2018230 (-) 294 WP_009854994.1 bacteriocin immunity protein -
  SGGBAA2069_RS10040 (SGGBAA2069_c19650) - 2018281..2018508 (-) 228 WP_013643481.1 hypothetical protein -
  SGGBAA2069_RS10045 (SGGBAA2069_c19670) - 2018777..2019088 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  SGGBAA2069_RS10050 (SGGBAA2069_c19680) - 2019100..2019249 (-) 150 WP_013643483.1 hypothetical protein -
  SGGBAA2069_RS10055 (SGGBAA2069_c19690) - 2019306..2019557 (-) 252 WP_231844599.1 DUF3884 family protein -
  SGGBAA2069_RS12190 (SGGBAA2069_c19710) - 2019858..2020028 (+) 171 WP_013643486.1 hypothetical protein -
  SGGBAA2069_RS10060 (SGGBAA2069_c19720) - 2020017..2021327 (-) 1311 WP_013643487.1 sensor histidine kinase -
  SGGBAA2069_RS10065 (SGGBAA2069_c19730) comE/comE1 2021332..2022063 (-) 732 WP_013643488.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 454 a.a.        Molecular weight: 52349.70 Da        Isoelectric Point: 5.3190

>NTDB_id=40068 SGGBAA2069_RS10025 WP_039695025.1 2015734..2017098(-) (comD/comD3) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MDLRSLIAFLETFVTFLGYAILFKSITKYRLAVWEWLVSVLVLPILASGFAVVMLLCFADMDGFKTVMIKNIVVLLWFTT
LSYRHDRSLLPRYHIFYGLFPVAVEDILLRTVSYSLAALFSTRINAIGQSWIAHVDIWTPVPIYFMASKLLEIDISNVKK
TLQNYLSSTSLILINLLMAFYFFGIDYVALKSPFGSVGSESFRERVTFVYIILLFLFLFYLNYKYVREQEIELQRQQELE
LISLENYSKHVESLYQEVRSFRHDYANILLSIGESIERNDLQTIKKIYNDITNDSEKFVKNSKFDLTRLSHISNSAIKSL
MSAKFLEAENLGITITLEVPEVVECPKIPLITYIRILAILFDNAIEAAVLSDVPKISVANFYQDDNFVFMIENSTKEDSI
PIDNIYQKGYSSKGDNRGIGLATVSEFQQEYDNLSIETSSSNHLFRQILRIYES

Nucleotide


Download         Length: 1365 bp        

>NTDB_id=40068 SGGBAA2069_RS10025 WP_039695025.1 2015734..2017098(-) (comD/comD3) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
TTGGATTTAAGGAGTTTAATTGCGTTTTTAGAAACCTTTGTCACGTTTTTGGGGTATGCTATCCTATTTAAGAGCATTAC
CAAGTACCGACTTGCCGTTTGGGAATGGCTAGTATCTGTTTTAGTGTTGCCAATTCTTGCATCAGGCTTTGCGGTTGTCA
TGCTTTTGTGCTTTGCGGATATGGACGGTTTCAAAACTGTCATGATTAAAAATATTGTGGTGTTGTTGTGGTTTACCACC
TTATCTTACCGTCATGATAGGTCCTTGCTACCAAGGTATCATATTTTTTATGGGCTTTTTCCAGTTGCGGTAGAGGATAT
TTTGCTTAGGACGGTGTCTTATTCATTAGCGGCGCTATTTTCCACAAGAATCAATGCTATCGGACAGTCATGGATTGCTC
ATGTTGACATCTGGACACCCGTTCCGATTTATTTTATGGCTTCAAAATTACTGGAAATTGATATTTCAAATGTCAAAAAG
ACCTTGCAAAATTACCTTAGCTCGACAAGTCTTATCTTGATTAATCTGCTAATGGCTTTCTACTTTTTTGGAATAGATTA
TGTCGCTTTGAAAAGTCCATTTGGTAGCGTAGGTAGTGAATCGTTTAGAGAAAGAGTTACTTTTGTTTACATTATTCTTC
TTTTTCTATTTTTGTTCTATCTGAATTACAAATACGTCCGTGAACAAGAGATAGAATTACAAAGGCAGCAGGAGCTAGAA
TTAATTTCGCTGGAAAATTACAGTAAACATGTGGAAAGTTTGTACCAAGAGGTCAGAAGTTTCAGACATGATTATGCCAA
TATTTTGTTGAGTATAGGAGAAAGTATCGAGCGAAATGACTTGCAAACTATCAAAAAAATCTATAATGACATTACTAATG
ATTCTGAGAAGTTCGTCAAAAATAGCAAATTCGATTTGACACGCTTGTCTCATATTTCAAATAGTGCCATCAAAAGTTTG
ATGTCTGCTAAATTTCTAGAGGCTGAAAATCTCGGAATCACCATTACTTTGGAAGTTCCTGAAGTCGTGGAGTGTCCCAA
AATTCCACTTATTACCTACATTCGCATCCTTGCTATCTTGTTTGATAATGCGATTGAAGCTGCGGTGTTATCAGATGTTC
CTAAAATATCCGTAGCGAATTTTTATCAAGATGATAACTTTGTTTTTATGATTGAAAATTCAACCAAAGAAGATAGTATT
CCGATTGATAATATTTATCAAAAAGGCTATTCAAGCAAAGGAGACAATCGTGGTATTGGCTTAGCAACAGTTAGTGAATT
TCAGCAAGAATATGACAATCTCTCCATTGAAACAAGCAGCTCAAATCACCTCTTTAGACAAATTTTGAGAATCTATGAAT
CCTAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(354-449)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

50.109

100

0.504
  comD/comD2 Streptococcus equinus JB1

57.372

68.722

0.394

Multiple sequence alignment