Detailed information NTG0040069

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: SGGBAA2069_RS10030
• Genome accession: NC_015215
• Coordinates: 2017111..2017839 (-)
• Length: 242 a.a.
• NCBI ID: WP_043913786.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2012111..2022839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS10000 (SGGBAA2069_c19590)	rpe	2012724..2013386 (-)	663	WP_013643476.1	ribulose-phosphate 3-epimerase	-
SGGBAA2069_RS10005 (SGGBAA2069_c19600)	rsgA	2013393..2014265 (-)	873	WP_013643477.1	ribosome small subunit-dependent GTPase A	-
SGGBAA2069_RS10020 (SGGBAA2069_c19610)	-	2015402..2015602 (-)	201	WP_013643478.1	hypothetical protein	-
SGGBAA2069_RS10025 (SGGBAA2069_c19620)	comD/comD3	2015734..2017098 (-)	1365	WP_039695025.1	GHKL domain-containing protein	Regulator
SGGBAA2069_RS10030 (SGGBAA2069_c19630)	comE/comE2	2017111..2017839 (-)	729	WP_043913786.1	LytR/AlgR family response regulator transcription factor	Regulator
SGGBAA2069_RS10035 (SGGBAA2069_c19640)	-	2017937..2018230 (-)	294	WP_009854994.1	bacteriocin immunity protein	-
SGGBAA2069_RS10040 (SGGBAA2069_c19650)	-	2018281..2018508 (-)	228	WP_013643481.1	hypothetical protein	-
SGGBAA2069_RS10045 (SGGBAA2069_c19670)	-	2018777..2019088 (-)	312	WP_003066564.1	bacteriocin immunity protein	-
SGGBAA2069_RS10050 (SGGBAA2069_c19680)	-	2019100..2019249 (-)	150	WP_013643483.1	hypothetical protein	-
SGGBAA2069_RS10055 (SGGBAA2069_c19690)	-	2019306..2019557 (-)	252	WP_231844599.1	DUF3884 family protein	-
SGGBAA2069_RS12190 (SGGBAA2069_c19710)	-	2019858..2020028 (+)	171	WP_013643486.1	hypothetical protein	-
SGGBAA2069_RS10060 (SGGBAA2069_c19720)	-	2020017..2021327 (-)	1311	WP_013643487.1	sensor histidine kinase	-
SGGBAA2069_RS10065 (SGGBAA2069_c19730)	comE/comE1	2021332..2022063 (-)	732	WP_013643488.1	response regulator transcription factor	Regulator
SGGBAA2069_RS10070	-	2022080..2022406 (-)	327	WP_009855002.1	LytTR family DNA-binding domain-containing protein	-

Sequence

Protein

• Length: 242 a.a.
• Molecular weight: 28053.35 Da
• Isoelectric Point: 6.7499

>NTDB_id=40069 SGGBAA2069_RS10030 WP_043913786.1 2017111..2017839(-) (comE/comE2) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MIDIYVLEDDVNQQFRLEKMIDEVLVDNQWQHRCFELFGEPSRLITLIDETFPQIFFLDLDINGDKTKGIEVAKAIRDVS
KTATIVFVTTHSEFTLLTYRAQVSALDFIDKTDSDLAIKENLQACLKKVVEGQVPRLSLDTFIFENNKTKIRIPFEDILY
FETAEAHRLMLVTRTGQRNFYGTIREVKKANHKLFQCHKSYLINPDNVVSLDKKEGLVYFAGGKSCYVSKKHMKELKTKL
ES

Nucleotide

• Length: 729 bp

>NTDB_id=40069 SGGBAA2069_RS10030 WP_043913786.1 2017111..2017839(-) (comE/comE2) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGATTGATATTTATGTTTTGGAAGATGACGTAAATCAGCAATTCCGCTTGGAAAAAATGATTGACGAGGTGCTTGTGGA
CAATCAGTGGCAACATCGTTGTTTTGAATTGTTTGGTGAGCCTAGTCGTCTTATCACTCTTATTGATGAAACATTTCCTC
AAATCTTTTTCTTAGATTTGGATATCAATGGTGATAAAACGAAAGGAATTGAAGTTGCCAAGGCGATTAGAGACGTTTCG
AAAACAGCAACGATTGTTTTTGTTACAACGCATTCTGAATTTACGCTCCTAACTTATCGTGCGCAAGTCAGTGCCCTTGA
TTTCATTGATAAAACTGACAGTGACTTGGCAATCAAGGAAAATTTGCAGGCTTGTTTAAAGAAAGTCGTTGAAGGACAAG
TGCCTCGCCTAAGCTTGGATACCTTTATTTTTGAAAACAATAAAACCAAAATCAGAATACCGTTTGAAGATATTCTTTAT
TTTGAAACGGCGGAAGCGCACCGTTTGATGTTGGTGACACGGACAGGACAGCGTAATTTTTACGGAACAATTAGAGAAGT
TAAAAAGGCAAATCATAAGCTATTTCAATGCCATAAATCCTATCTGATTAATCCTGATAATGTCGTCAGTTTGGATAAAA
AAGAAGGACTTGTTTATTTTGCAGGTGGAAAATCTTGCTACGTTTCCAAAAAACACATGAAAGAATTAAAAACTAAACTA
GAAAGTTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-113)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus equinus JB1	70.661	100	0.707
comE/comE1	Streptococcus equinus JB1	43.802	100	0.438
comE/blpR	Streptococcus mutans UA159	42.739	99.587	0.426