Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SGGBAA2069_RS09150 Genome accession   NC_015215
Coordinates   1840370..1841062 (-) Length   230 a.a.
NCBI ID   WP_009854820.1    Uniprot ID   A0A139QWD3
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1835370..1846062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS09130 (SGGBAA2069_c17800) dnaI 1836146..1837048 (-) 903 WP_009854816.1 primosomal protein DnaI -
  SGGBAA2069_RS09135 (SGGBAA2069_c17810) - 1837059..1838216 (-) 1158 WP_013643364.1 DnaD domain protein -
  SGGBAA2069_RS09140 (SGGBAA2069_c17820) nrdR 1838200..1838697 (-) 498 WP_013643365.1 transcriptional regulator NrdR -
  SGGBAA2069_RS09145 (SGGBAA2069_c17830) - 1838886..1840370 (-) 1485 WP_012962415.1 ATP-binding protein -
  SGGBAA2069_RS09150 (SGGBAA2069_c17840) covR 1840370..1841062 (-) 693 WP_009854820.1 response regulator transcription factor Regulator
  SGGBAA2069_RS09155 (SGGBAA2069_c17850) - 1841298..1841834 (-) 537 WP_013643366.1 YceD family protein -
  SGGBAA2069_RS09160 (SGGBAA2069_c17860) htpX 1841972..1842874 (-) 903 WP_013643367.1 zinc metalloprotease HtpX -
  SGGBAA2069_RS09165 (SGGBAA2069_c17870) - 1843001..1843552 (-) 552 WP_012962418.1 LemA family protein -
  SGGBAA2069_RS09170 (SGGBAA2069_c17890) rsmG 1843883..1844596 (+) 714 WP_043913877.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  SGGBAA2069_RS09175 (SGGBAA2069_c17900) - 1844666..1846039 (+) 1374 WP_013643370.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26487.39 Da        Isoelectric Point: 4.7059

>NTDB_id=40064 SGGBAA2069_RS09150 WP_009854820.1 1840370..1841062(-) (covR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSQGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=40064 SGGBAA2069_RS09150 WP_009854820.1 1840370..1841062(-) (covR) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGCTTTGTGTCTTTGGAGTTACAACATGAAGGTTA
TTCTGTGGTTGTAGAAACAAACGGGCGCTTAGGGCTTCAAACGGCTCTTGATGACGATTTTGACTTGATTTTGCTTGATT
TAATGCTTCCAGATATGGATGGATTTGAAATCACGCGTCGTCTTCGATTGGAAAAAGAAACTTCTATTATTATGATGACA
GCTCGCGACTCTATTATGGATATTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTCAAACCATTTGCAATTGA
AGAACTCTTGGCTCGTGTTCGTGCTGTTTTCCGCCGTCAAGACGTTGAATCTAAACGTGAACAAGACAGTCAAGGAAAAG
AAGGATTGCTTGGTCTACGCTTAAATCCTCAAAATCGTTCAGCGGTTCGAGGTGATGATGAAATTTCGCTTACAAAACGT
GAGTACGATTTGTTAAGTGTTCTTTTGTCAAATGTTAATCGTGTAATGACACGTGAAGAACTGCTAGCCAGTGTTTGGAG
ATACGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QWD3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.422

Multiple sequence alignment