Detailed information NTG0397534

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: HRE60_RS06780
• Genome accession: NZ_CP054153
• Coordinates: 1542493..1543137 (-)
• Length: 214 a.a.
• NCBI ID: WP_002884791.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain DB-B5
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1537493..1548137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRE60_RS06755 (HRE60_06755)	-	1539569..1540567 (-)	999	WP_181670546.1	NAD(P)/FAD-dependent oxidoreductase	-
HRE60_RS06760 (HRE60_06760)	trmD	1540569..1541288 (-)	720	WP_181670547.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
HRE60_RS06765 (HRE60_06765)	rimM	1541278..1541796 (-)	519	WP_002884411.1	ribosome maturation factor RimM	-
HRE60_RS06780 (HRE60_06780)	vraR	1542493..1543137 (-)	645	WP_002884791.1	response regulator transcription factor	Regulator
HRE60_RS06785 (HRE60_06785)	-	1543127..1544137 (-)	1011	WP_181670548.1	sensor histidine kinase	-
HRE60_RS06790 (HRE60_06790)	liaF	1544134..1544832 (-)	699	WP_181670549.1	cell wall-active antibiotics response protein LiaF	-
HRE60_RS06795 (HRE60_06795)	-	1544995..1545753 (-)	759	WP_002884314.1	potassium channel family protein	-
HRE60_RS06800 (HRE60_06800)	stkP/pknB	1545902..1547776 (-)	1875	WP_181670550.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 23977.31 Da
• Isoelectric Point: 4.5814

>NTDB_id=397534 HRE60_RS06780 WP_002884791.1 1542493..1543137(-) (vraR) [Streptococcus salivarius strain DB-B5]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide

• Length: 645 bp

>NTDB_id=397534 HRE60_RS06780 WP_002884791.1 1542493..1543137(-) (vraR) [Streptococcus salivarius strain DB-B5]
ATGTCGAATAAGATTAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGACTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTCGTTGGAGAGGCAGGGAATGGTCGAGAGGGTGTCGATCTTGCCTTGGAACTGCGTCCGGATGTCG
TCGTTATGGACCTTGTTATGCCTGAATTAGATGGTGTTCAAGCAACTTTGGAATTGCTCAAAGAGTGGCCTGAAGCCAAG
ATTTTAGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATCGAAGCTGGTGCTAAAGGCTATATGCTTAA
AACTAGTAGTGCAGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTGACGGCACGTGAACGAGATATCTTGGCCCTTTTG
GCTAAGGGGTATGACAATCAAACTATTGCTAACGAGCTATTTATTTCATTGAAGACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGCACTCAGGCTGTCGTTTATGCTTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

• Response regulator receiver domain (Response_reg) (7-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	50.485	96.262	0.486
degU	Bacillus subtilis subsp. subtilis str. 168	36.161	100	0.379