Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HRE60_RS05840 Genome accession   NZ_CP054153
Coordinates   1222062..1223846 (-) Length   594 a.a.
NCBI ID   WP_037600702.1    Uniprot ID   -
Organism   Streptococcus salivarius strain DB-B5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1217062..1228846
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS05820 (HRE60_05820) cls 1217244..1218794 (-) 1551 WP_172855714.1 cardiolipin synthase -
  HRE60_RS05825 (HRE60_05825) - 1219387..1220937 (+) 1551 WP_002885312.1 BCCT family transporter -
  HRE60_RS05830 (HRE60_05830) - 1221129..1221497 (+) 369 WP_080551210.1 potassium channel family protein -
  HRE60_RS05835 (HRE60_05835) - 1221510..1221749 (-) 240 WP_002885362.1 protein rep -
  HRE60_RS05840 (HRE60_05840) uvrC 1222062..1223846 (-) 1785 WP_037600702.1 excinuclease ABC subunit UvrC Machinery gene
  HRE60_RS05845 (HRE60_05845) - 1223918..1224613 (-) 696 WP_048675436.1 YjjG family noncanonical pyrimidine nucleotidase -
  HRE60_RS05850 (HRE60_05850) sdaAB 1224889..1225560 (+) 672 WP_002891207.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  HRE60_RS05855 (HRE60_05855) sdaAA 1225573..1226442 (+) 870 WP_002891209.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68584.99 Da        Isoelectric Point: 9.4604

>NTDB_id=397530 HRE60_RS05840 WP_037600702.1 1222062..1223846(-) (uvrC) [Streptococcus salivarius strain DB-B5]
MNNLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDDKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDLAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRKELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKHFK
SMTAIQKASAEDIQALGIPEKVAEALLDKLNDNN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=397530 HRE60_RS05840 WP_037600702.1 1222062..1223846(-) (uvrC) [Streptococcus salivarius strain DB-B5]
ATGAATAATCTGATTAAACATAAGCTGGAATTGCTCCCAAACAACCCGGGGTGCTATCTCCACAAGGACAAATTCGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACTAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCCAATATTGAGGCCCTGCTTTTGGAAATTAAT
CTTATCCAAGAGAATATGCCTAAATTCAACATCCGTCTCAAGGATGACAAGTCTTATCCATTTATCAAGATTACTAAGGA
GCTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGCGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CGGCCAATGAAATCAAGAAGCTTTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCGGCCAATAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAAGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAATCAGCTTAAGGCCAAGATGAAGGATATGTCTGACCAGATGG
AGTTTGAGCGTGCTGCGGAGTATCGCGATTTGATTGAGGCGGTTTCGACGCTTAGGACCAAGCAAAGGGTTATCCGTCAA
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGATAAGGGGTGGATGTGTGTTCAGGTTTTCTTTGTTCGCCAAGG
GAAACTCATTCAGCGTGATGTCAATATGTTCCCTTATTATAATGATGCTGAGGAAGATTTCCTAACCTATATGGGTCAGT
TTTATCTGGATAGTCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGAGACATTGATCAAGAGTCTGTTGAGGCTCTA
GTTGGAGATGAGGTCAAGGTCTTTAAACCTCAACGTGGAGAGAAGAAGCAGTTGGTTAATCTGGCGACGAAAAATGCCCG
CGTCAGTTTGACCCAAAAATTTGATCTCCTCGAAAAAGACTTGGCTAAGACCCAAGGAGCTATTGAAAATCTAGGCAAAC
TCATGGGGATTCCGACACCGGTCCGTATCGAGTCTTTCGATAACTCTAATATCATGGGAACTAGCCCTGTCTCTGCCATG
GTTGTCTTTGAAAATGGTAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACTGTTGAAGGCCCTGACGATTA
TGCCAGTATGCGTGAGGTCATTCGTCGTCGCTATAGTCGTGTCAAACGTGATGGTCTAACGCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTAGCCAAGGATGTGCTTCGCAAGGAACTCAATCTATCTATCCCAGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTTTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGTCAAGTCCGTAGTA
AGAATAGTTTCAGTTCTAAACTTGATGGCGTGGAGGGGTTAGGACCTAAGCGCAAACAAAAACTTCTCAAACACTTCAAG
TCTATGACAGCTATCCAAAAAGCCAGTGCCGAAGACATTCAAGCTCTTGGAATCCCTGAAAAAGTAGCAGAGGCTCTGTT
AGATAAATTAAATGATAACAATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.819

99.495

0.764
  uvrC Streptococcus pneumoniae R6

76.481

99.495

0.761
  uvrC Streptococcus pneumoniae D39

76.481

99.495

0.761

Multiple sequence alignment