Detailed information NTG0039748

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: TTJL18_RS08345
• Genome accession: NC_017587
• Coordinates: 1554783..1555757 (+)
• Length: 324 a.a.
• NCBI ID: WP_011227913.1
• Uniprot ID: Q5SL87
• Organism: Thermus thermophilus JL-18
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1549783..1560757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTJL18_RS08315 (TtJL18_1670)	-	1550447..1550974 (-)	528	Protein_1639	IS630 family transposase	-
TTJL18_RS08320	-	1550949..1551488 (-)	540	WP_261975815.1	IS630 family transposase	-
TTJL18_RS13115	-	1551639..1551902 (+)	264	WP_187287946.1	hypothetical protein	-
TTJL18_RS08330 (TtJL18_1672)	-	1552108..1553001 (-)	894	WP_014630112.1	site-specific DNA-methyltransferase	-
TTJL18_RS08335 (TtJL18_1673)	-	1552998..1553924 (-)	927	WP_014630113.1	RluA family pseudouridine synthase	-
TTJL18_RS08340 (TtJL18_1674)	panB	1553972..1554757 (-)	786	WP_014630114.1	3-methyl-2-oxobutanoate hydroxymethyltransferase	-
TTJL18_RS08345 (TtJL18_1675)	ruvB	1554783..1555757 (+)	975	WP_011227913.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
TTJL18_RS08350 (TtJL18_1676)	-	1555754..1556785 (+)	1032	WP_014630115.1	DUF4388 domain-containing protein	-
TTJL18_RS08355 (TtJL18_1677)	-	1556806..1558158 (-)	1353	WP_014630116.1	tetratricopeptide repeat protein	-
TTJL18_RS08360 (TtJL18_1678)	ftsH	1558231..1560087 (+)	1857	WP_014630117.1	ATP-dependent zinc metalloprotease FtsH	-
TTJL18_RS08365 (TtJL18_1679)	-	1560073..1560501 (-)	429	WP_014630118.1	hypothetical protein	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 35973.74 Da
• Isoelectric Point: 6.3232

>NTDB_id=39748 TTJL18_RS08345 WP_011227913.1 1554783..1555757(+) (ruvB) [Thermus thermophilus JL-18]
MEDLALRPKTLDEYIGQERLKQKLRVYLEAAKARKEPLEHLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDL
AAILANSLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIVIGQGPAARTIRLELPRFTLIGATTRPGLITAPLLSRFG
IVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGRRSRGTMRVAKRLFRRVRDFAQVAGEEVITRERALEALAALGL
DELGLEKRDREILEVLILRFGGGPVGLATLATALSEDPGTLEEVHEPYLIRQGLLKRTPRGRVATELAYRHLGYPPPVGP
LLEP

Nucleotide

• Length: 975 bp

>NTDB_id=39748 TTJL18_RS08345 WP_011227913.1 1554783..1555757(+) (ruvB) [Thermus thermophilus JL-18]
GTGGAAGACCTCGCCCTTAGGCCCAAGACCCTGGACGAGTACATCGGCCAGGAACGCCTGAAGCAAAAGCTCCGGGTCTA
CCTCGAGGCGGCCAAGGCCCGAAAAGAGCCCTTGGAGCACCTCCTCCTCTTCGGCCCCCCGGGCCTGGGCAAGACCACCC
TGGCCCACGTCATCGCCCACGAGCTTGGGGTCAACCTCCGGGTCACCTCCGGGCCCGCCATAGAGAAGCCCGGGGACCTC
GCCGCCATCCTGGCCAACTCCCTGGAGGAAGGGGACATCCTCTTCATTGACGAGATCCACCGCCTGAGCCGCCAGGCCGA
GGAGCACCTCTACCCCGCCATGGAGGACTTCGTCATGGACATCGTCATCGGCCAAGGTCCGGCGGCGAGAACCATCCGGC
TGGAGCTTCCCCGCTTCACCCTGATCGGGGCCACCACCCGGCCCGGCCTGATCACCGCGCCCCTCTTGAGCCGCTTCGGC
ATCGTGGAGCACCTGGAGTACTACACCCCCGAGGAGCTGGCCCAAGGGGTGATGCGGGACGCCCGCCTCCTCGGGGTGAG
GATCACGGAGGAGGCCGCCCTGGAGATCGGTAGGCGGAGCCGGGGCACCATGCGCGTCGCCAAGCGCCTCTTCCGGAGGG
TGCGGGACTTCGCCCAGGTGGCGGGGGAGGAGGTCATCACCCGGGAGCGGGCCCTGGAGGCCCTTGCGGCCCTGGGCCTG
GACGAGCTGGGCTTGGAGAAGCGGGACCGGGAGATCCTGGAGGTCCTCATCCTCCGCTTCGGCGGTGGCCCAGTGGGCCT
CGCCACCTTGGCCACCGCCCTCTCCGAGGACCCGGGCACCTTGGAAGAGGTGCACGAGCCCTACCTCATCCGCCAGGGCC
TTTTGAAGCGCACTCCCCGGGGCCGGGTGGCCACGGAACTGGCCTACCGCCACCTGGGCTACCCGCCCCCGGTGGGCCCC
CTCTTGGAGCCGTGA

Domains

Predicted by InterProScan.

• RuvB AAA lid domain (AAA_lid_4) (168-241)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (6-165)

• RuvB C-terminal winged helix domain (WHD_RuvB) (242-312)

3D structure

• PDB: 1HQC
• PDB: 1IXR
• PDB: 1IXS
• PDB: 8EFV
• PDB: 8EFY

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Bacillus subtilis subsp. subtilis str. 168	59.105	96.605	0.571
ruvB	Streptococcus pneumoniae TIGR4	56.774	95.679	0.543
ruvB	Streptococcus pneumoniae R6	56.774	95.679	0.543
ruvB	Streptococcus pneumoniae D39	56.774	95.679	0.543
ruvB	Synechocystis sp. PCC 6803	50.779	99.074	0.503
ruvB	Helicobacter pylori 26695	50.637	96.914	0.491