Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA2   Type   Machinery gene
Locus tag   TSC_RS12595 Genome accession   NC_014974
Coordinates   710453..711013 (-) Length   186 a.a.
NCBI ID   WP_081454907.1    Uniprot ID   A0A430RWW5
Organism   Thermus scotoductus SA-01     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 705453..716013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TSC_RS03765 (TSC_c07690) - 706394..707095 (+) 702 WP_015716676.1 chromosome segregation protein ScpA -
  TSC_RS12585 (TSC_c07700) - 707150..707515 (+) 366 WP_015716677.1 nucleotidyltransferase family protein -
  TSC_RS13425 - 707500..707859 (-) 360 WP_041438121.1 type II secretion system protein -
  TSC_RS03780 (TSC_c07710) comZ 708078..709700 (-) 1623 WP_321162868.1 competence protein ComZ Machinery gene
  TSC_RS12590 pilA/pilA3 709752..710456 (-) 705 WP_081454906.1 PilW family protein Machinery gene
  TSC_RS12595 pilA/pilA2 710453..711013 (-) 561 WP_081454907.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  TSC_RS03785 (TSC_c07720) - 711010..711480 (-) 471 WP_041438123.1 GspH/FimT family protein -
  TSC_RS03790 (TSC_c07730) pilA/pilA1 711534..712004 (-) 471 WP_015716680.1 GspH/FimT family protein Machinery gene
  TSC_RS03795 (TSC_c07740) - 712075..713265 (+) 1191 WP_015716681.1 thiolase family protein -
  TSC_RS03800 (TSC_c07750) - 713366..713674 (-) 309 WP_015716682.1 DUF503 domain-containing protein -
  TSC_RS03805 (TSC_c07760) - 713731..714090 (-) 360 WP_015716683.1 DUF86 domain-containing protein -
  TSC_RS03810 (TSC_c07770) - 714087..714392 (-) 306 WP_015716684.1 nucleotidyltransferase family protein -

Sequence

Protein


Download         Length: 186 a.a.        Molecular weight: 20279.05 Da        Isoelectric Point: 8.1039

>NTDB_id=39733 TSC_RS12595 WP_081454907.1 710453..711013(-) (pilA/pilA2) [Thermus scotoductus SA-01]
MRRQGLTLLETLIALAVLGIAFGALLMSQLSNLRVSAQSRYATDAKAAAIRVLEQKSSEVLRSEILQPPSVYIDDPSTNR
SFYFVDYFYGCPSRVNPAFPLRDGSQNNLRQVRCSGQEQEGNSSVEWLIFGESGTLGEGVVTIVVTATHDRGPKITMGRR
VTCYDVYPSPTQDKPAPCPPPGGGRP

Nucleotide


Download         Length: 561 bp        

>NTDB_id=39733 TSC_RS12595 WP_081454907.1 710453..711013(-) (pilA/pilA2) [Thermus scotoductus SA-01]
ATGAGAAGGCAAGGCTTGACGCTTTTGGAAACCCTAATCGCCCTGGCTGTTTTGGGCATTGCCTTTGGGGCCCTGCTCAT
GAGCCAGCTATCCAACCTGCGGGTTTCAGCTCAGAGCCGTTATGCCACTGACGCCAAGGCAGCAGCGATACGGGTTCTGG
AACAAAAGTCCTCTGAGGTATTAAGAAGTGAGATACTACAGCCTCCGAGTGTTTACATAGACGACCCCAGCACCAACCGC
AGCTTTTACTTTGTGGACTACTTTTATGGCTGCCCAAGTCGTGTAAATCCCGCATTCCCCTTAAGAGACGGCAGCCAAAA
CAACTTACGTCAAGTGCGTTGCTCTGGTCAAGAACAGGAGGGCAACTCTTCTGTAGAGTGGCTAATATTCGGTGAAAGCG
GGACCTTAGGCGAAGGGGTAGTAACCATTGTGGTCACTGCTACCCATGATCGCGGCCCAAAAATAACCATGGGCAGGCGG
GTGACGTGTTATGACGTTTATCCTTCACCCACCCAGGACAAACCCGCCCCCTGTCCTCCTCCGGGAGGTGGTCGTCCGTG
A

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(2-26)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A430RWW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA2 Thermus thermophilus HB27

63.441

100

0.634

Multiple sequence alignment