Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   TSC_RS12310 Genome accession   NC_014974
Coordinates   2340637..2342700 (+) Length   687 a.a.
NCBI ID   WP_015718358.1    Uniprot ID   E8PQY9
Organism   Thermus scotoductus SA-01     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2335637..2347700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TSC_RS12270 (TSC_c24930) - 2335644..2336099 (+) 456 WP_015718349.1 hypothetical protein -
  TSC_RS12275 (TSC_c24940) pfkA 2336148..2337116 (-) 969 WP_015718350.1 6-phosphofructokinase -
  TSC_RS12280 (TSC_c24950) rsmI 2337113..2337931 (-) 819 WP_015718351.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  TSC_RS12285 (TSC_c24960) - 2337933..2338430 (-) 498 WP_015718352.1 TFIIB-type zinc ribbon-containing protein -
  TSC_RS12290 (TSC_c24970) - 2338514..2339044 (-) 531 WP_015718353.1 inorganic diphosphatase -
  TSC_RS12295 (TSC_c24980) - 2339055..2339705 (-) 651 WP_015718354.1 glycerophosphodiester phosphodiesterase -
  TSC_RS13510 (TSC_c24990) - 2339729..2340223 (+) 495 WP_015718355.1 YcxB family protein -
  TSC_RS13380 (TSC_c25000) - 2340208..2340369 (+) 162 WP_015718356.1 hypothetical protein -
  TSC_RS12305 (TSC_c25010) comEA 2340342..2340650 (+) 309 WP_015718357.1 helix-hairpin-helix domain-containing protein Machinery gene
  TSC_RS12310 (TSC_c25020) comA/comEC 2340637..2342700 (+) 2064 WP_015718358.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  TSC_RS12315 (TSC_c25030) - 2342688..2343500 (-) 813 WP_015718359.1 ParB/RepB/Spo0J family partition protein -
  TSC_RS12320 (TSC_c25040) soj 2343484..2344236 (-) 753 WP_015718360.1 chromosome-partitioning ATPase Soj -
  TSC_RS12325 (TSC_c25050) rsmG 2344230..2344958 (-) 729 WP_172959258.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  TSC_RS12330 (TSC_c25060) mnmG 2344995..2346788 (-) 1794 WP_015718362.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 687 a.a.        Molecular weight: 73438.91 Da        Isoelectric Point: 9.9763

>NTDB_id=39731 TSC_RS12310 WP_015718358.1 2340637..2342700(+) (comA/comEC) [Thermus scotoductus SA-01]
MSGPRAFFPKPPLSTWGPGVGLGLGGLLGAWGLFHPWVLLLAPLLLPFLRLPFALGLVFVLLRGLLFPVPEPPYGTRLEG
VFTLHQGTILWQGHRLWVQHYPGLEDGRYRLRGYLAPPQGKRNPGGFDQRTWLLSRGIRGVFHVERAEALAPLPDPRAPW
RERLTAGLSPQVGEVVEGLVLGDKRGLEDAYPLFQKAGLAHLLAVSGQNVGYLAATLALLPLGRWRYLLALLLLPAYLWL
AGPSPSLLRASLMAGLSLLGLFLGLGAAGVFQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALALPSGARGW
LLGGLAASLAAQLPLIPLLLHHFAFLPLLAPLVNLLALPLAALLVPLGLLKLLLGGVLAPLVEALARALLALAQVASQGP
LLRWGEVSPPGFALYYLALLPPFLVLRGLFPWRKALLLATLPVLAGLAAGWPKPLDLWALDVGQGDALLARMGGAEVLVD
GGRPEQGEKVVRALRALGVEALEVLVATHPDVDHYGGLLQVVAELPVGLALLSPAFPRDHPLVRALEAKGVPIRYPGAGT
RLRVGRGSLEVLWPPGPQADDNQGGLVLLLDFVGPKALLLADVPGEVEERLTPPQVAVVKVSHHGSRTGTDEDLLERTRP
QVALIGVGRNPHGHPHPEVLERLDQHGVRVYRTDQNGAVRVLFGYAW

Nucleotide


Download         Length: 2064 bp        

>NTDB_id=39731 TSC_RS12310 WP_015718358.1 2340637..2342700(+) (comA/comEC) [Thermus scotoductus SA-01]
ATGTCCGGCCCTAGGGCATTCTTCCCCAAGCCTCCCCTCTCTACCTGGGGTCCAGGGGTAGGCCTGGGTCTAGGCGGGCT
CCTGGGAGCCTGGGGGCTTTTCCATCCCTGGGTCCTTCTCCTGGCGCCCTTACTCCTCCCCTTCCTCCGGCTTCCCTTCG
CCCTTGGGCTCGTTTTTGTCCTCCTCCGGGGCCTCCTCTTCCCCGTACCGGAACCCCCTTACGGCACCCGCCTCGAGGGT
GTCTTCACCCTCCACCAAGGCACCATCCTCTGGCAGGGGCACAGGCTCTGGGTGCAGCACTACCCGGGCCTGGAGGATGG
CCGCTACCGGCTGAGGGGGTACCTGGCTCCACCCCAGGGCAAGCGCAACCCCGGGGGCTTTGACCAGCGCACCTGGCTCC
TCTCCCGGGGGATAAGAGGGGTGTTTCACGTGGAACGGGCGGAGGCCCTGGCCCCCCTACCCGATCCTCGGGCACCCTGG
CGAGAGCGCCTCACCGCGGGCCTCTCCCCCCAGGTCGGGGAAGTGGTGGAGGGCCTGGTCCTAGGGGACAAAAGGGGCCT
CGAGGACGCCTACCCCCTCTTCCAGAAAGCGGGCCTCGCCCACCTCCTTGCGGTCTCCGGGCAGAACGTGGGCTATTTGG
CGGCGACCCTAGCCCTTCTTCCCCTGGGGCGGTGGCGCTACCTCCTCGCCCTCCTCCTTCTCCCCGCCTACCTGTGGCTG
GCAGGCCCCAGCCCCTCCCTGCTGCGGGCGAGCCTCATGGCGGGCCTTTCCCTCCTGGGGCTCTTCCTCGGCCTGGGAGC
CGCGGGGGTCTTCCAGGCCTTGGGGTTGGCCCTTTTCCTCCAACTCCTCCTCCGCCCCGAGGCCCTCCTGGGCCTAGGCT
TCCAGCTCTCCTACCTGGCGGTGCTGGGCCTGGCCCTGGTCCTCCCCGCCTTGGCCCTTCCCTCAGGGGCCCGGGGCTGG
CTCCTCGGGGGCCTCGCCGCCAGCCTGGCCGCCCAGCTCCCCCTTATCCCCCTCCTCCTCCACCACTTCGCCTTCCTCCC
CCTCCTCGCCCCCCTGGTCAACCTCCTTGCCCTCCCCCTGGCGGCCCTCCTCGTGCCCCTGGGTCTTCTGAAGCTCCTCC
TTGGGGGAGTCCTGGCGCCCCTGGTGGAAGCCCTGGCCCGAGCCCTCCTGGCCCTGGCTCAGGTCGCCTCCCAAGGACCC
CTGCTCCGGTGGGGGGAGGTCTCGCCCCCGGGCTTTGCCCTTTACTACCTGGCCCTCCTGCCTCCCTTCCTCGTCCTCCG
CGGGCTCTTCCCCTGGCGCAAGGCCCTCCTCCTCGCCACCCTGCCCGTCCTGGCTGGCCTCGCCGCCGGCTGGCCCAAAC
CCTTGGACCTCTGGGCCCTGGACGTGGGCCAGGGGGATGCCCTGCTGGCCCGCATGGGCGGGGCCGAGGTGCTGGTGGAC
GGGGGCCGGCCCGAGCAGGGGGAAAAGGTGGTGCGGGCCCTAAGGGCCCTGGGGGTGGAAGCCCTGGAGGTCCTGGTGGC
CACCCACCCCGACGTGGACCACTACGGCGGGCTCCTCCAGGTGGTGGCCGAGCTCCCGGTGGGCCTGGCCCTCCTCTCCC
CGGCCTTTCCCCGGGATCACCCCTTGGTGCGGGCTCTGGAGGCCAAGGGGGTACCCATCCGCTACCCCGGCGCGGGCACG
CGGCTCAGGGTGGGGCGGGGGAGCCTCGAGGTCCTCTGGCCTCCTGGCCCGCAAGCAGACGACAACCAAGGCGGTCTGGT
CCTCCTCCTGGACTTCGTCGGGCCCAAAGCCCTTCTCCTGGCAGACGTGCCCGGGGAGGTGGAGGAAAGGCTCACTCCCC
CGCAGGTGGCGGTGGTTAAGGTTAGCCACCACGGCTCCCGCACGGGCACGGACGAGGACCTCCTGGAACGCACCCGACCC
CAGGTGGCCTTGATAGGCGTGGGAAGGAACCCCCATGGCCACCCCCACCCCGAGGTCTTGGAGCGCCTGGACCAGCATGG
GGTAAGGGTCTACCGCACCGACCAAAACGGCGCGGTGCGGGTCCTCTTTGGCTACGCCTGGTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(108-148)

Metallo-beta-lactamase superfamily (Lactamase_B)

(462-645)

Competence protein (Competence)

(179-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E8PQY9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

71.852

98.253

0.706

Multiple sequence alignment