Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GH742_RS04530 Genome accession   NZ_CP045732
Coordinates   950357..951016 (+) Length   219 a.a.
NCBI ID   WP_058525608.1    Uniprot ID   A0AB38N4P1
Organism   Legionella sp. MW5194     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 945357..956016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GH742_RS04510 (GH742_04495) comFC 946425..947114 (-) 690 WP_239005279.1 ComF family protein Machinery gene
  GH742_RS04515 (GH742_04500) bioC 947150..948007 (+) 858 WP_203456285.1 malonyl-ACP O-methyltransferase BioC -
  GH742_RS04520 (GH742_04505) - 948115..949338 (+) 1224 WP_203456286.1 sterol desaturase family protein -
  GH742_RS04525 (GH742_04510) phhA 949412..950230 (+) 819 WP_203456287.1 phenylalanine 4-monooxygenase -
  GH742_RS04530 (GH742_04515) letA 950357..951016 (+) 660 WP_058525608.1 two-component system response regulator LetA Regulator
  GH742_RS04535 (GH742_04520) uvrC 951061..952920 (+) 1860 WP_203456288.1 excinuclease ABC subunit UvrC -
  GH742_RS04540 (GH742_04525) - 952969..955500 (-) 2532 WP_203456289.1 EAL domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24626.92 Da        Isoelectric Point: 5.8066

>NTDB_id=396427 GH742_RS04530 WP_058525608.1 950357..951016(+) (letA) [Legionella sp. MW5194]
MIKVLIVDDHALVRMGIRRLLDDLPDMEVVAEAENGEQALTLVKTCKPDVVLLDMKMPGIDGWEVTRRLKKSNPQIKIIA
VTAMCAEPLPTRILQLGAMGYLTKESGAQEMAAAIRKVAKGEKYLSAEIAQKMAINSLEAVEESPFDRLSEREMQVMFMI
TSGMTVQDIADRLFLSSKTINGYRYRMFDKLGIKNDVELTFLAMKHRIIEKPTDALHDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=396427 GH742_RS04530 WP_058525608.1 950357..951016(+) (letA) [Legionella sp. MW5194]
TTGATCAAAGTACTAATTGTTGATGACCATGCCTTGGTTAGAATGGGTATTCGACGATTATTAGACGACTTACCTGACAT
GGAAGTGGTCGCTGAAGCAGAGAATGGAGAGCAGGCTCTCACCCTGGTGAAGACCTGTAAACCGGATGTCGTGTTATTGG
ACATGAAAATGCCTGGCATTGATGGTTGGGAGGTGACGCGCCGTCTTAAAAAATCCAATCCGCAAATTAAAATCATCGCC
GTTACCGCCATGTGTGCCGAGCCTCTGCCTACCCGCATTTTGCAGCTCGGAGCCATGGGTTATCTAACCAAAGAATCCGG
TGCTCAGGAAATGGCTGCCGCCATACGCAAGGTGGCGAAAGGGGAAAAGTATTTAAGTGCCGAAATTGCCCAGAAAATGG
CAATCAACAGCCTCGAAGCCGTTGAAGAATCACCGTTTGATCGTTTGTCTGAACGCGAAATGCAGGTGATGTTCATGATT
ACCAGCGGCATGACGGTACAGGATATCGCTGATCGCTTGTTTTTAAGCAGCAAAACCATTAATGGCTACCGCTACCGCAT
GTTCGATAAATTGGGCATTAAAAACGATGTGGAATTAACCTTCCTGGCCATGAAACACCGAATCATTGAAAAACCCACGG
ATGCCTTGCACGATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

84.475

100

0.845
  letA Legionella pneumophila strain ERS1305867

84.475

100

0.845

Multiple sequence alignment