Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   GFB63_RS01850 Genome accession   NZ_CP045596
Coordinates   376738..377433 (-) Length   231 a.a.
NCBI ID   WP_023909867.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 371738..382433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS01835 (GFB63_01890) - 371858..373106 (+) 1249 Protein_375 ISL3 family transposase -
  GFB63_RS01840 (GFB63_01895) - 373154..374422 (-) 1269 WP_084829025.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GFB63_RS01845 (GFB63_01900) - 374508..376748 (-) 2241 WP_100262540.1 DNA internalization-related competence protein ComEC/Rec2 -
  GFB63_RS01850 (GFB63_01905) comEA 376738..377433 (-) 696 WP_023909867.1 helix-hairpin-helix domain-containing protein Machinery gene
  GFB63_RS01855 (GFB63_01910) - 377541..378296 (-) 756 WP_011681497.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  GFB63_RS01860 (GFB63_01915) - 378425..379360 (+) 936 WP_193838358.1 polysaccharide deacetylase family protein -
  GFB63_RS01865 (GFB63_01920) - 379410..380174 (+) 765 WP_011681498.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  GFB63_RS01870 (GFB63_01925) - 380178..380447 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24539.52 Da        Isoelectric Point: 4.7259

>NTDB_id=395449 GFB63_RS01850 WP_023909867.1 376738..377433(-) (comEA) [Streptococcus thermophilus strain TK-P3A]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQRSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=395449 GFB63_RS01850 WP_023909867.1 376738..377433(-) (comEA) [Streptococcus thermophilus strain TK-P3A]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGATCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.567

100

0.996
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

40.175

99.134

0.398
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.281

98.701

0.368

Multiple sequence alignment