Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   SGGB_RS00650 Genome accession   NC_017576
Coordinates   101767..102060 (+) Length   97 a.a.
NCBI ID   WP_012961329.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96767..107060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS00625 (SGGB_0086) - 98758..99126 (+) 369 WP_009853228.1 DUF1033 family protein -
  SGGB_RS00630 (SGGB_0087) comGA 99197..100138 (+) 942 WP_012961327.1 competence type IV pilus ATPase ComGA Machinery gene
  SGGB_RS00635 (SGGB_0088) comGB 100020..101105 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  SGGB_RS00640 (SGGB_0089) comGC 101105..101398 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  SGGB_RS00645 (SGGB_0090) comGD 101382..101813 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SGGB_RS00650 (SGGB_0091) comGE 101767..102060 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE Machinery gene
  SGGB_RS00655 (SGGB_0092) comGF 102014..102481 (+) 468 WP_014619875.1 competence type IV pilus minor pilin ComGF Machinery gene
  SGGB_RS00660 (SGGB_0093) comGG 102453..102767 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  SGGB_RS00665 (SGGB_0094) comGH 102840..103796 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  SGGB_RS00670 (SGGB_0095) - 103849..105048 (+) 1200 WP_009853237.1 acetate kinase -
  SGGB_RS00675 (SGGB_0096) - 105279..105479 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  SGGB_RS00680 (SGGB_0097) - 105489..105698 (+) 210 WP_009853239.1 hypothetical protein -
  SGGB_RS00685 (SGGB_0098) - 105711..106163 (+) 453 WP_009853240.1 hypothetical protein -
  SGGB_RS00690 (SGGB_0099) - 106175..106813 (+) 639 WP_009853241.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10952.89 Da        Isoelectric Point: 8.4757

>NTDB_id=39508 SGGB_RS00650 WP_012961329.1 101767..102060(+) (comGE) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQSMQESLRQQEALNVATMAVQTGQNHLKMNGVEVEIIKKDG
EVYVYEGKTEILHVKKD

Nucleotide


Download         Length: 294 bp        

>NTDB_id=39508 SGGB_RS00650 WP_012961329.1 101767..102060(+) (comGE) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTCTATGCAAGAAAGTTTACGGCAGCAGGAAGCTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGACAAAATCATTTGAAGATGAATGGTGTTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

47.917

98.969

0.474
  comGE Streptococcus mutans UA159

47.917

98.969

0.474
  comGE/cglE Streptococcus mitis SK321

42.553

96.907

0.412
  comGE/cglE Streptococcus pneumoniae Rx1

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae R6

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

41.489

96.907

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

41.489

96.907

0.402

Multiple sequence alignment