Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   GE021_RS07085 Genome accession   NZ_CP053792
Coordinates   1421476..1423719 (-) Length   747 a.a.
NCBI ID   WP_125074384.1    Uniprot ID   A0A3P5XQ11
Organism   Streptococcus canis strain HL_77_1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1416476..1428719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS07065 (GE021_007065) - 1416892..1418112 (+) 1221 WP_125074388.1 DUF3114 domain-containing protein -
  GE021_RS07070 (GE021_007070) - 1418427..1419488 (-) 1062 WP_172774140.1 serine hydrolase -
  GE021_RS07075 (GE021_007075) sodA 1419654..1420259 (-) 606 WP_125074386.1 superoxide dismutase SodA -
  GE021_RS07080 (GE021_007080) holA 1420356..1421396 (-) 1041 WP_125074385.1 DNA polymerase III subunit delta -
  GE021_RS07085 (GE021_007085) comEC/celB 1421476..1423719 (-) 2244 WP_125074384.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GE021_RS07090 (GE021_007090) comEA 1423700..1424362 (-) 663 WP_125074383.1 ComEA family DNA-binding protein Machinery gene
  GE021_RS07095 (GE021_007095) - 1424565..1425305 (-) 741 WP_164407398.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  GE021_RS07100 (GE021_007100) - 1425423..1426199 (+) 777 WP_125074621.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  GE021_RS07105 (GE021_007105) - 1426189..1426467 (+) 279 WP_003044201.1 GIY-YIG nuclease family protein -
  GE021_RS07110 (GE021_007110) - 1426595..1428595 (-) 2001 WP_125074622.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 85080.95 Da        Isoelectric Point: 9.7677

>NTDB_id=394630 GE021_RS07085 WP_125074384.1 1421476..1423719(-) (comEC/celB) [Streptococcus canis strain HL_77_1]
MTFSWTKLLPLPKIQLAFLVLVLFYHIYSPGWLTSLLGLGLICLLVKRLSKREFLSVFAILSLSALFLLYQKQQLTQELE
TQPLQITSVELIPDSIRINGDQLAVIGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVLHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQMEQLEVSSPKSVFDYLSSLRRQAIVHCQQHFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTYFRRLLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACAFLLVFL
WDAHFLMTVGGVLTFSYAFMLTIVTVEELSGAKRQLVQALIISLGMLPLLLFYFSSFNPMSIILTGLLSYLFDVLILPLL
CLVFCLSPLVTVSVCNHLFLLLEKGIQFLGNTVNTSLVFGSPTSWQLLLIVLSFAILYDYRQVRQRVFTCGLVITLTLLS
VKYPLTNEVTIVDIGQGDSILIRDWRGKTLLIDVGGRPTFSKKEKWRSGYQTANAQKTLIPYLKSRGIHKIDQLLLTHTD
ADHMGDMEVVAKAIRVKEVLTSQGSLTNPSAVQRLNRLKCQIKVVKAGDQLSIMGSTLQVLYPWKLGDGKNNDSLVLYGK
LLNRTFLFTGDLEKEGEVEIIKRYPQLRVDYLKAGHHGSNTSSSAVFLDHLQPKLAFISAGKNNRYHHPSKETLTRLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=394630 GE021_RS07085 WP_125074384.1 1421476..1423719(-) (comEC/celB) [Streptococcus canis strain HL_77_1]
ATGACATTTTCTTGGACTAAGCTATTGCCCCTGCCAAAGATTCAATTAGCTTTCTTGGTTTTGGTTCTCTTTTATCACAT
TTATAGTCCTGGCTGGTTAACTTCTCTTCTTGGCCTTGGTTTGATTTGCTTACTTGTAAAGCGTTTGTCTAAAAGAGAAT
TTCTCAGTGTCTTTGCCATCCTTAGTTTATCTGCTTTGTTTTTACTCTATCAGAAACAACAGCTGACTCAAGAACTGGAG
ACTCAGCCATTACAAATAACCTCTGTAGAATTGATTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTATTGG
ACGTCATGGGAAACACTCCTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAAAAAGAACACC
GTTGGTTAGTGCTGCACGCAAAAGTGACCTTGGAAAAAGCTGAGGAGGTTCGCAATTTTAAAGGATTTAATTACCAGACT
TTTTTGGCTTATCAGGGAATTTACAGGATAGGGAAGGTAGAGCAAATGGAACAACTTGAAGTGAGCTCTCCAAAGTCAGT
GTTTGATTACTTGTCTTCCTTAAGACGGCAGGCCATTGTCCATTGTCAACAGCATTTTCCTAAACCCATGTCTCACTACC
TGACAGGTCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGCCAGCTGGGCATCATTCAT
CTTTTTGCCTTATCAGGGATGCAGGTTGGTTTCTTTCTCACTTATTTTAGAAGGTTGTTGCTATTACTAGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGCTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGCATAAAAGGTTTAGACAATCTCGCTTGTGCTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGGGTATTAACATTTAGCTATGCTTTTATGTTAACAATAGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGCGCTAATTATCTCCCTAGGAATGTTACCGTTACTGCTTTTTTATT
TTTCCAGTTTTAATCCGATGTCAATAATATTAACAGGTCTCTTGTCTTACCTCTTTGACGTTTTGATTTTGCCTCTTCTT
TGTCTGGTTTTCTGTCTATCCCCTCTGGTGACTGTCTCAGTATGCAATCATCTCTTTCTTTTATTAGAAAAGGGGATTCA
ATTTCTTGGAAATACTGTCAATACTTCCCTTGTTTTTGGAAGTCCAACTAGTTGGCAATTACTTCTTATAGTGCTCAGCT
TTGCAATTCTTTATGACTATCGACAGGTGCGACAAAGGGTCTTCACTTGTGGATTGGTCATAACATTGACCTTACTGTCT
GTCAAATACCCTTTGACAAATGAAGTCACTATCGTTGATATTGGACAAGGAGATAGTATTTTGATAAGGGATTGGCGAGG
AAAGACACTCTTGATAGACGTTGGAGGACGTCCAACCTTTTCTAAAAAGGAGAAATGGCGCAGCGGTTATCAGACGGCGA
ATGCCCAAAAAACCTTAATCCCTTATTTAAAAAGCAGAGGCATTCATAAAATTGATCAGTTATTACTAACTCATACGGAT
GCTGATCACATGGGAGATATGGAAGTGGTTGCCAAAGCCATTCGAGTGAAGGAAGTGTTAACTAGCCAAGGTAGTTTAAC
GAACCCAAGTGCTGTGCAACGTTTAAACCGTTTGAAATGTCAGATTAAGGTTGTTAAAGCTGGCGACCAGTTGTCCATTA
TGGGAAGCACCTTGCAGGTCCTCTATCCTTGGAAATTAGGAGATGGAAAAAATAATGATTCTTTGGTCCTCTATGGCAAG
CTATTAAATCGAACTTTTCTTTTCACAGGGGACTTGGAAAAAGAAGGAGAAGTTGAGATTATCAAACGTTATCCCCAGTT
AAGGGTGGATTATTTGAAAGCTGGCCATCATGGGTCAAATACTTCTTCAAGTGCAGTTTTTTTAGACCATCTTCAGCCCA
AGCTTGCTTTTATTTCTGCAGGAAAGAATAATCGGTACCACCATCCTAGTAAAGAGACCTTAACACGTTTGGAAGACAGA
CAAATCACGTATTATCGAACTGATACTCAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

Competence protein (Competence)

(217-462)

Metallo-beta-lactamase superfamily (Lactamase_B)

(495-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5XQ11

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

46.917

99.866

0.469
  comEC/celB Streptococcus mitis NCTC 12261

46.577

99.732

0.465
  comEC/celB Streptococcus pneumoniae TIGR4

45.174

99.866

0.451
  comEC/celB Streptococcus pneumoniae Rx1

44.906

99.866

0.448
  comEC/celB Streptococcus pneumoniae D39

44.906

99.866

0.448
  comEC/celB Streptococcus pneumoniae R6

44.906

99.866

0.448
  comEC Lactococcus lactis subsp. cremoris KW2

42.013

99.732

0.419