Detailed information NTG0393338

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GCS73_RS03655
• Genome accession: NZ_CP045308
• Coordinates: 714384..715457 (+)
• Length: 357 a.a.
• NCBI ID: WP_003632878.1
• Uniprot ID: D3HQ04
• Organism: Legionella longbeachae strain B41211CHC
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 709384..720457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCS73_RS03630 (GCS73_03600)	-	709685..710440 (-)	756	WP_003632883.1	CPBP family glutamic-type intramembrane protease	-
GCS73_RS03635 (GCS73_03605)	rsmB	710437..711813 (-)	1377	WP_003632882.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
GCS73_RS03640 (GCS73_03610)	fmt	711800..712753 (-)	954	WP_003632881.1	methionyl-tRNA formyltransferase	-
GCS73_RS03645 (GCS73_03615)	def	712750..713262 (-)	513	WP_003632880.1	peptide deformylase	-
GCS73_RS03650 (GCS73_03620)	-	713350..714387 (+)	1038	WP_003632879.1	LysM peptidoglycan-binding domain-containing protein	-
GCS73_RS03655 (GCS73_03625)	dprA	714384..715457 (+)	1074	WP_003632878.1	DNA-processing protein DprA	Machinery gene
GCS73_RS03660 (GCS73_03630)	-	715461..715895 (+)	435	WP_003632877.1	DUF494 family protein	-
GCS73_RS03665 (GCS73_03635)	topA	716028..718307 (+)	2280	WP_003632876.1	type I DNA topoisomerase	-
GCS73_RS03670	-	718480..718641 (-)	162	WP_003632875.1	hypothetical protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 38676.91 Da
• Isoelectric Point: 7.1617

>NTDB_id=393338 GCS73_RS03655 WP_003632878.1 714384..715457(+) (dprA) [Legionella longbeachae strain B41211CHC]
MSNLLFYLALNRMEQVGPRTVMKLRKRWPDLQQMFGLTATELEQAGVSGSLAQTITGFDFSLIQMDLHWLNAAEDHHLLT
WDSPEYPALLKEITDPPLVLYAKGQLSCLQQPKLAIVGSRNPTVTGSENARMFAKSISAYGVTIVSGLALGIDAQAHMGC
LEAGGQTIAVLGTGIDCIYPHRHVTLSQQISQNGLLLSEFPLKSPPIAGHFPRRNRIISGLSLCTLVVESAVKSGSLITA
RMALEQNRDVLAIPGSIHNPMARGCHYLLQQGAKLVTSVADVLEELMIDSKGQTTSKAILPLASGNKNLVKFIGFEMTTV
DQIILRSGCTVEQVTRELAELELSGVVVSVPGGYMRC

Nucleotide

• Length: 1074 bp

>NTDB_id=393338 GCS73_RS03655 WP_003632878.1 714384..715457(+) (dprA) [Legionella longbeachae strain B41211CHC]
ATGAGTAATTTACTCTTTTATCTGGCTTTAAACCGTATGGAACAAGTTGGCCCACGTACCGTGATGAAGCTACGTAAACG
CTGGCCTGATTTACAACAAATGTTTGGGCTTACAGCAACGGAGTTGGAACAAGCGGGAGTATCTGGTTCTTTGGCGCAAA
CCATAACTGGTTTTGATTTCAGTTTGATCCAAATGGATTTACATTGGTTAAATGCTGCAGAAGATCATCATCTATTGACT
TGGGATTCACCTGAATATCCCGCACTCTTAAAAGAAATTACTGATCCACCCCTGGTTTTATATGCTAAAGGCCAACTTTC
CTGTTTGCAGCAGCCAAAGCTTGCTATAGTGGGAAGTCGGAATCCAACTGTAACGGGTAGTGAGAATGCACGGATGTTTG
CAAAATCAATTTCGGCTTATGGTGTTACAATTGTAAGTGGCCTGGCTTTAGGAATTGATGCTCAGGCCCATATGGGATGT
TTGGAAGCTGGAGGCCAAACAATTGCTGTTCTGGGCACGGGAATTGATTGTATTTATCCACATCGACATGTAACACTTTC
GCAACAGATTAGTCAAAATGGTCTTCTATTAAGCGAATTTCCCTTAAAAAGTCCACCAATCGCTGGACATTTCCCGAGAA
GAAATCGTATAATAAGTGGTTTATCATTGTGCACTTTGGTTGTTGAGTCAGCAGTGAAAAGTGGCTCATTAATCACAGCA
CGAATGGCCTTGGAACAAAATCGCGATGTTTTGGCGATTCCAGGCTCCATTCATAATCCTATGGCTCGAGGTTGTCATTA
CCTATTACAGCAAGGAGCTAAGTTAGTGACGTCAGTTGCTGATGTTCTCGAGGAGTTAATGATTGATTCAAAAGGGCAAA
CAACGAGTAAAGCAATTTTACCTCTTGCCAGCGGGAATAAAAACCTAGTAAAGTTCATTGGTTTTGAAATGACTACTGTT
GATCAGATCATTTTACGTAGTGGATGCACCGTTGAGCAAGTGACTCGTGAGCTTGCAGAATTAGAATTGAGTGGGGTTGT
TGTATCTGTCCCCGGTGGCTATATGAGGTGTTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-277)

• DprA winged helix domain (DprA_WH) (299-353)

3D structure

• AlphaFold DB: D3HQ04

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	73.109	100	0.731
dprA	Vibrio campbellii strain DS40M4	46.364	92.437	0.429
dprA	Vibrio cholerae strain A1552	41.918	100	0.429
dprA	Glaesserella parasuis strain SC1401	38.667	100	0.406
dprA	Acinetobacter baylyi ADP1	37.607	98.319	0.37