Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NLA_RS07075 Genome accession   NC_014752
Coordinates   1486526..1487191 (-) Length   221 a.a.
NCBI ID   WP_013449153.1    Uniprot ID   E4ZDY8
Organism   Neisseria lactamica 020-06     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1481526..1492191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLA_RS07040 (NLA_13460) dut 1482219..1482671 (-) 453 WP_013449149.1 dUTP diphosphatase -
  NLA_RS07045 (NLA_13470) - 1482813..1483523 (+) 711 WP_036469214.1 AzlC family ABC transporter permease -
  NLA_RS07050 (NLA_13480) - 1483520..1483828 (+) 309 WP_003707454.1 AzlD family protein -
  NLA_RS07055 (NLA_13490) pilL 1483898..1484371 (-) 474 WP_025457170.1 PilX family type IV pilin Machinery gene
  NLA_RS07060 (NLA_13500) pilK 1484373..1484969 (-) 597 WP_003707450.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  NLA_RS07065 (NLA_13510) pilJ 1484948..1485889 (-) 942 WP_013449151.1 PilW family protein Machinery gene
  NLA_RS07070 (NLA_13520) pilI 1485886..1486497 (-) 612 WP_013449152.1 type IV pilus modification protein PilV Machinery gene
  NLA_RS07075 (NLA_13530) pilH 1486526..1487191 (-) 666 WP_013449153.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NLA_RS07080 (NLA_13540) dnaB 1487336..1488748 (-) 1413 WP_013449154.1 replicative DNA helicase -
  NLA_RS07085 (NLA_13550) - 1488914..1489495 (+) 582 WP_013449155.1 superoxide dismutase -
  NLA_RS07090 (NLA_13560) - 1489560..1489892 (-) 333 WP_013449156.1 hypothetical protein -
  NLA_RS07095 (NLA_13570) cysT 1490079..1490915 (+) 837 WP_013449157.1 sulfate ABC transporter permease subunit CysT -
  NLA_RS07100 (NLA_13580) cysW 1491303..1492163 (+) 861 WP_013449158.1 sulfate ABC transporter permease subunit CysW -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24551.08 Da        Isoelectric Point: 9.1812

>NTDB_id=39071 NLA_RS07075 WP_013449153.1 1486526..1487191(-) (pilH) [Neisseria lactamica 020-06]
MCTRKQQGFTLIELLIVMVIAAIMAMIALPSMSRWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGTVN
NQCDFSKKGQGMLAFGDKNGNKAYDGDAADVFLRSVVLNDADDSRINYAFNHIAFGRTQPTADRVVWTFNQNGAFGYSSD
QNLTRTSRFVYSDGYIQIVLTDAKAVSADEKKFRSAVVLIDGSGRVEVCPRNDMRAVCQHQ

Nucleotide


Download         Length: 666 bp        

>NTDB_id=39071 NLA_RS07075 WP_013449153.1 1486526..1487191(-) (pilH) [Neisseria lactamica 020-06]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAATAGAGCTGCTCATCGTGATGGTCATCGCAGCCATTATGGCGATGAT
AGCCCTCCCCAGTATGAGCCGGTGGATTGCATCCCGCCGCATCGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGGTCAAC
AACCAATGCGACTTCAGTAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGCAGCGTGGTGTTGAATGATGCCGACGACAGCCGGATTAATTATGCCTTCAACCATATCG
CTTTCGGTCGGACACAGCCGACTGCCGACCGTGTTGTTTGGACTTTCAACCAAAACGGGGCATTCGGCTATTCGTCCGAT
CAGAATCTCACGCGCACTTCCAGATTTGTTTACTCTGACGGCTATATCCAAATCGTGTTGACAGATGCGAAGGCGGTTTC
TGCCGATGAAAAGAAATTCCGTTCGGCAGTGGTTTTGATTGACGGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACGATA
TGCGCGCCGTATGCCAACATCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-177)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E4ZDY8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.455

99.548

0.851

Multiple sequence alignment