Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   F8B64_RS04045 Genome accession   NZ_CP044497
Coordinates   776088..776780 (+) Length   230 a.a.
NCBI ID   WP_005666688.1    Uniprot ID   -
Organism   Haemophilus influenzae strain PittGG     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 771088..781780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F8B64_RS04025 (F8B64_04025) ampD 772356..772919 (-) 564 WP_012054949.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  F8B64_RS04030 (F8B64_04030) pilA 773034..773483 (+) 450 WP_012054948.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  F8B64_RS04035 (F8B64_04035) pilB 773480..774874 (+) 1395 WP_012054947.1 GspE/PulE family protein Machinery gene
  F8B64_RS04040 (F8B64_04040) pilC 774871..776091 (+) 1221 WP_012054946.1 type II secretion system F family protein Machinery gene
  F8B64_RS04045 (F8B64_04045) pilD 776088..776780 (+) 693 WP_005666688.1 A24 family peptidase Machinery gene
  F8B64_RS04050 (F8B64_04050) rho 776835..778097 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  F8B64_RS04055 (F8B64_04055) metJ 778345..778662 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  F8B64_RS04060 (F8B64_04060) cueR 778676..779062 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  F8B64_RS04065 (F8B64_04065) - 779139..779345 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  F8B64_RS04070 (F8B64_04070) - 779419..779625 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  F8B64_RS04075 (F8B64_04075) - 779711..779917 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  F8B64_RS04080 (F8B64_04080) - 780003..780209 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26779.80 Da        Isoelectric Point: 8.8544

>NTDB_id=390515 F8B64_RS04045 WP_005666688.1 776088..776780(+) (pilD) [Haemophilus influenzae strain PittGG]
MIYFAMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLSFQPSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=390515 F8B64_RS04045 WP_005666688.1 776088..776780(+) (pilD) [Haemophilus influenzae strain PittGG]
ATGATTTACTTCGCAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGTCATTTCAGCCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGCTACTTACAATCGGTTTATTTGGGGCAGACAATAATTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGGCGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTGTTATTAGCTTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCAGTCATCATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90.435

100

0.904
  pilD Haemophilus influenzae Rd KW20

90

100

0.9

Multiple sequence alignment