Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FSA40_RS08970 Genome accession   NZ_CP044493
Coordinates   1768067..1768759 (-) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1763067..1773759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS08945 - 1763129..1763754 (-) 626 Protein_1669 HI_0552 family protein -
  FSA40_RS08950 (FSA40_1797) der 1763829..1765138 (-) 1310 Protein_1670 ribosome biogenesis GTPase Der -
  FSA40_RS08955 (FSA40_1798) dnaI 1765151..1766050 (-) 900 WP_002265120.1 primosomal protein DnaI -
  FSA40_RS08960 (FSA40_1799) - 1766051..1767220 (-) 1170 WP_151416434.1 DnaD domain protein -
  FSA40_RS08965 (FSA40_1800) nrdR 1767207..1767698 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  FSA40_RS08970 (FSA40_1801) covR 1768067..1768759 (-) 693 WP_002262121.1 response regulator GcrR Regulator
  FSA40_RS08975 (FSA40_1802) - 1769115..1769651 (-) 537 WP_002262122.1 YceD family protein -
  FSA40_RS08980 (FSA40_1803) - 1769644..1770219 (-) 576 WP_002274867.1 TetR/AcrR family transcriptional regulator -
  FSA40_RS08985 (FSA40_1804) - 1770327..1771034 (+) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  FSA40_RS08990 (FSA40_1805) - 1771036..1773648 (+) 2613 WP_151416435.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=390392 FSA40_RS08970 WP_002262121.1 1768067..1768759(-) (covR) [Streptococcus mutans strain MD]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=390392 FSA40_RS08970 WP_002262121.1 1768067..1768759(-) (covR) [Streptococcus mutans strain MD]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment