Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FSA31_RS08685 Genome accession   NZ_CP044492
Coordinates   1734758..1735450 (-) Length   230 a.a.
NCBI ID   WP_002284742.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1729758..1740450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS08660 (FSA31_1714) - 1729817..1730443 (-) 627 WP_002268642.1 hypothetical protein -
  FSA31_RS08665 (FSA31_1715) der 1730518..1731828 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  FSA31_RS08670 (FSA31_1716) dnaI 1731841..1732740 (-) 900 WP_002284744.1 primosomal protein DnaI -
  FSA31_RS08675 (FSA31_1717) - 1732741..1733910 (-) 1170 WP_002284743.1 DnaD domain protein -
  FSA31_RS08680 (FSA31_1718) nrdR 1733897..1734388 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  FSA31_RS08685 (FSA31_1719) covR 1734758..1735450 (-) 693 WP_002284742.1 response regulator GcrR Regulator
  FSA31_RS08690 (FSA31_1720) - 1735806..1736342 (-) 537 WP_019802823.1 YceD family protein -
  FSA31_RS08695 (FSA31_1721) - 1736335..1736910 (-) 576 WP_002284740.1 TetR/AcrR family transcriptional regulator -
  FSA31_RS08700 (FSA31_1722) - 1737018..1737725 (+) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  FSA31_RS08705 (FSA31_1723) - 1737727..1740339 (+) 2613 WP_002284739.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=390320 FSA31_RS08685 WP_002284742.1 1734758..1735450(-) (covR) [Streptococcus mutans strain T8]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLLLLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=390320 FSA31_RS08685 WP_002284742.1 1734758..1735450(-) (covR) [Streptococcus mutans strain T8]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGTCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCCTCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCTGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

77.632

99.13

0.77
  covR Lactococcus lactis subsp. lactis strain DGCC12653

62.996

98.696

0.622
  vicR Streptococcus mutans UA159

42.424

100

0.426
  micA Streptococcus pneumoniae Cp1015

41.202

100

0.417

Multiple sequence alignment