Detailed information NTG0390288

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FSA31_RS02985
• Genome accession: NZ_CP044492
• Coordinates: 602204..604438 (+)
• Length: 744 a.a.
• NCBI ID: WP_002284906.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain T8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 597204..609438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA31_RS02960 (FSA31_0585)	-	597906..598925 (-)	1020	WP_002284908.1	GIY-YIG nuclease family protein	-
FSA31_RS02965 (FSA31_0586)	-	598971..599483 (-)	513	WP_002284907.1	HXXEE domain-containing protein	-
FSA31_RS02970 (FSA31_0587)	-	599568..600503 (-)	936	WP_002267102.1	polysaccharide deacetylase family protein	-
FSA31_RS02975 (FSA31_0588)	-	600642..601394 (+)	753	WP_002267103.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FSA31_RS02980 (FSA31_0589)	-	601534..602214 (+)	681	WP_002267104.1	helix-hairpin-helix domain-containing protein	-
FSA31_RS02985 (FSA31_0590)	comEC/celB	602204..604438 (+)	2235	WP_002284906.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FSA31_RS02990 (FSA31_0591)	-	604624..605250 (+)	627	WP_002264731.1	DUF805 domain-containing protein	-
FSA31_RS02995 (FSA31_0592)	holA	605418..606458 (+)	1041	WP_002270598.1	DNA polymerase III subunit delta	-
FSA31_RS03000 (FSA31_0593)	sodA	606604..607215 (+)	612	WP_002261912.1	superoxide dismutase SodA	-
FSA31_RS03005 (FSA31_0594)	-	607768..608823 (+)	1056	WP_019802650.1	serine hydrolase	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85580.00 Da
• Isoelectric Point: 10.0891

>NTDB_id=390288 FSA31_RS02985 WP_002284906.1 602204..604438(+) (comEC/celB) [Streptococcus mutans strain T8]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSVNGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSGILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRRRISDTNAEKTLIPYLKSRGIDKFDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=390288 FSA31_RS02985 WP_002284906.1 602204..604438(+) (comEC/celB) [Streptococcus mutans strain T8]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTGTCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCGGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTTACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTGCCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTGGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACTTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATACTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGTTTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (214-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	51.147	99.597	0.509
comEC/celB	Streptococcus mitis NCTC 12261	51.078	99.731	0.509
comEC/celB	Streptococcus pneumoniae TIGR4	50.672	100	0.507
comEC/celB	Streptococcus pneumoniae Rx1	50	100	0.5
comEC/celB	Streptococcus pneumoniae D39	50	100	0.5
comEC/celB	Streptococcus pneumoniae R6	50	100	0.5
comEC	Lactococcus lactis subsp. cremoris KW2	45.968	100	0.46