Detailed information NTG0389469

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: HHM66_RS06855
• Genome accession: NZ_CP053074
• Coordinates: 1391771..1394014 (-)
• Length: 747 a.a.
• NCBI ID: WP_046159328.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1386771..1399014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM66_RS06835 (HHM66_06840)	-	1387380..1388600 (+)	1221	WP_003056368.1	DUF3114 domain-containing protein	-
HHM66_RS06840 (HHM66_06845)	-	1388721..1389782 (-)	1062	WP_015057805.1	serine hydrolase	-
HHM66_RS06845 (HHM66_06850)	sodA	1389949..1390554 (-)	606	WP_015057806.1	superoxide dismutase SodA	-
HHM66_RS06850 (HHM66_06855)	holA	1390644..1391690 (-)	1047	WP_015057807.1	DNA polymerase III subunit delta	-
HHM66_RS06855 (HHM66_06860)	comEC/celB	1391771..1394014 (-)	2244	WP_046159328.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HHM66_RS06860 (HHM66_06865)	-	1393995..1394657 (-)	663	WP_015057863.1	helix-hairpin-helix domain-containing protein	-
HHM66_RS06865 (HHM66_06870)	-	1395054..1395794 (-)	741	WP_003062277.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
HHM66_RS06870 (HHM66_06875)	-	1395912..1396688 (+)	777	WP_003059826.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
HHM66_RS06875 (HHM66_06880)	-	1396678..1396956 (+)	279	WP_003061674.1	GIY-YIG nuclease family protein	-
HHM66_RS06880 (HHM66_06885)	-	1396980..1398980 (-)	2001	WP_015057865.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85150.67 Da
• Isoelectric Point: 9.2618

>NTDB_id=389469 HHM66_RS06855 WP_046159328.1 1391771..1394014(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MNYRWTKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQKTLCKVVMILALFAAVFVYRKHQLRQQLE
TQPLQVSQVALVPDSIRINGDQLAVIGRHGNHSYQLFYHFKHQTEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLDNLACAFLLVLL
WDAHALMTVGGVLTFSYAFMLTVITFEELSGVKKHFVQVITVSLGMLPFLLFYFASFNPMSMVLTELLSYLFDVLILPLL
CLIFCLSPLITLSGCNYLFLFLEKVIQFLGNTLNASLVFGSPTSWHLLILVISFAILYDHRKIRQRVITCGLVIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRGLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGNGKNNDSLVLYGR
LLNQTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLTRLEDR
EISYYRTDIQGAVRLTGWLNWHIETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=389469 HHM66_RS06855 WP_046159328.1 1391771..1394014(-) (comEC/celB) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGAACTATCGTTGGACTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGTTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAGAAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATCGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTAGTTCCTGATAGTATTCGAATTAATGGAGATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCATTTTAAACATCAAACGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTTTCACCAAAGTCAGT
AGGAGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGCCAACAATCCTTTCCAAAGCCCATGTCTCATTATT
TGACGGGACTCCTTTTCGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTATCAGGGATGCAGGTTGGCTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAGCTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGCATAAAAGGCTTAGATAATCTGGCTTGCGCTTTCTTACTTGTTCTTTTA
TGGGATGCTCATGCTTTGATGACTGTTGGTGGAGTACTAACATTTAGCTATGCGTTTATGTTAACTGTTATCACTTTTGA
GGAGTTATCGGGAGTTAAAAAGCATTTCGTCCAGGTCATTACTGTTTCTTTAGGGATGTTACCTTTCTTGCTCTTTTATT
TTGCTAGTTTTAACCCCATGTCAATGGTATTGACAGAGCTTTTGTCTTATCTCTTCGATGTTTTGATTTTGCCTCTTCTT
TGCTTGATTTTCTGTTTGTCTCCTTTGATAACTCTCTCAGGATGTAATTATCTCTTTCTTTTCTTAGAAAAAGTCATTCA
ATTTCTTGGGAATACCCTCAATGCCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCACTTGCTTATCCTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGAAGATACGACAAAGAGTTATCACTTGCGGCTTGGTCATAGGCCTGACGCTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGCGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCAAGCTTTGTTAGGCGGTTAAGGGGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTATCCTTGGCAGTTAGGGAACGGGAAAAATAACGATTCTCTGGTTCTTTATGGTAGG
CTCCTCAATCAAACTTTTCTATTTACAGGTGATTTGGAAAAAGAGGGAGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTAGAGGATAGG
GAAATTTCTTATTATCGCACGGATATTCAAGGAGCTGTTCGGTTGACAGGATGGCTAAATTGGCATATTGAGACTGTTCG
TTGA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	45.772	99.732	0.456
comEC/celB	Streptococcus mitis NCTC 12261	45.71	99.866	0.456
comEC/celB	Streptococcus pneumoniae TIGR4	45.187	100	0.452
comEC/celB	Streptococcus pneumoniae Rx1	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae D39	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae R6	44.92	100	0.45
comEC	Lactococcus lactis subsp. cremoris KW2	41.588	99.465	0.414