Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FOB62_RS10545 Genome accession   NZ_CP044102
Coordinates   2122045..2123355 (+) Length   436 a.a.
NCBI ID   WP_014612303.1    Uniprot ID   A0A9X8T438
Organism   Streptococcus dysgalactiae strain FDAARGOS_654     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2117045..2128355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB62_RS10530 (FOB62_10535) phoU 2117817..2118470 (+) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  FOB62_RS10535 (FOB62_10540) - 2118671..2121174 (+) 2504 Protein_2033 M1 family metallopeptidase -
  FOB62_RS10540 (FOB62_10545) ciaR 2121378..2122052 (+) 675 WP_014612304.1 response regulator transcription factor Regulator
  FOB62_RS10545 (FOB62_10550) ciaH 2122045..2123355 (+) 1311 WP_014612303.1 HAMP domain-containing sensor histidine kinase Regulator
  FOB62_RS10550 (FOB62_10555) rpsT 2123513..2123761 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  FOB62_RS10555 (FOB62_10560) coaA 2123815..2124735 (-) 921 WP_003058858.1 type I pantothenate kinase -
  FOB62_RS10560 (FOB62_10565) - 2125004..2125603 (+) 600 WP_138128085.1 class I SAM-dependent methyltransferase -
  FOB62_RS10565 (FOB62_10570) - 2125590..2126867 (+) 1278 WP_014612301.1 pyrimidine-nucleoside phosphorylase -
  FOB62_RS10570 (FOB62_10575) deoC 2126883..2127545 (+) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  FOB62_RS10575 (FOB62_10580) - 2127532..2127921 (+) 390 WP_003058840.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49918.49 Da        Isoelectric Point: 8.2375

>NTDB_id=387898 FOB62_RS10545 WP_014612303.1 2122045..2123355(+) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_654]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSIDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=387898 FOB62_RS10545 WP_014612303.1 2122045..2123355(+) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTATCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514

Multiple sequence alignment