Detailed information NTG0387701

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FOB77_RS10790
• Genome accession: NZ_CP044091
• Coordinates: 2060101..2062338 (-)
• Length: 745 a.a.
• NCBI ID: WP_000939916.1
• Uniprot ID: A0AAW6XU20
• Organism: Streptococcus agalactiae strain FDAARGOS_669
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2055101..2067338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB77_RS10765 (FOB77_10765)	holA	2055165..2056202 (-)	1038	WP_000560292.1	DNA polymerase III subunit delta	-
FOB77_RS10770 (FOB77_10770)	-	2056256..2056984 (-)	729	WP_000468965.1	bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG	-
FOB77_RS10775 (FOB77_10775)	-	2057160..2058152 (+)	993	WP_000800994.1	alpha/beta hydrolase fold domain-containing protein	-
FOB77_RS10780 (FOB77_10780)	-	2058211..2059155 (-)	945	WP_000200825.1	LacI family DNA-binding transcriptional regulator	-
FOB77_RS10785 (FOB77_10785)	-	2059166..2059975 (-)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
FOB77_RS10790 (FOB77_10790)	comEC/celB	2060101..2062338 (-)	2238	WP_000939916.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FOB77_RS10795 (FOB77_10795)	-	2062322..2062975 (-)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
FOB77_RS10800 (FOB77_10800)	-	2063073..2063813 (-)	741	WP_000500220.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FOB77_RS10805 (FOB77_10805)	-	2063948..2064712 (+)	765	WP_000567423.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FOB77_RS10810 (FOB77_10810)	-	2064705..2064971 (+)	267	WP_000598736.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85548.47 Da
• Isoelectric Point: 9.7741

>NTDB_id=387701 FOB77_RS10790 WP_000939916.1 2060101..2062338(-) (comEC/celB) [Streptococcus agalactiae strain FDAARGOS_669]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLGCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=387701 FOB77_RS10790 WP_000939916.1 2060101..2062338(-) (comEC/celB) [Streptococcus agalactiae strain FDAARGOS_669]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTATACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAGGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTTTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

• Competence protein (Competence) (215-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.469	100	0.489
comEC/celB	Streptococcus mitis NCTC 12261	48.267	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.004	100	0.474
comEC/celB	Streptococcus pneumoniae Rx1	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.533	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.533	100	0.468
comEC	Lactococcus lactis subsp. cremoris KW2	44.145	99.732	0.44