Detailed information NTG0385839

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: F1539_RS05385
• Genome accession: NZ_CP043772
• Coordinates: 1026550..1027242 (+)
• Length: 230 a.a.
• NCBI ID: WP_013525531.1
• Uniprot ID: A0AAV2U3Y4
• Organism: Haemophilus influenzae biotype aegyptius strain HE24/F3037
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1021550..1032242

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F1539_RS05365 (F1539_05370)	ampD	1022824..1023384 (-)	561	WP_006996183.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
F1539_RS05370 (F1539_05375)	pilA	1023499..1023948 (+)	450	WP_006996184.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
F1539_RS05375 (F1539_05380)	pilB	1023945..1025339 (+)	1395	WP_013525533.1	GspE/PulE family protein	Machinery gene
F1539_RS05380 (F1539_05385)	-	1025336..1026553 (+)	1218	Protein_1052	type II secretion system F family protein	-
F1539_RS05385 (F1539_05390)	pilD	1026550..1027242 (+)	693	WP_013525531.1	A24 family peptidase	Machinery gene
F1539_RS05390 (F1539_05395)	rho	1027297..1028559 (-)	1263	WP_005666690.1	transcription termination factor Rho	-
F1539_RS05395 (F1539_05400)	metJ	1028807..1029124 (+)	318	WP_005631186.1	met regulon transcriptional regulator MetJ	-
F1539_RS05400 (F1539_05405)	cueR	1029138..1029524 (-)	387	WP_005648963.1	Cu(I)-responsive transcriptional regulator	-
F1539_RS05405 (F1539_05410)	-	1029601..1029807 (+)	207	WP_013525530.1	heavy-metal-associated domain-containing protein	-
F1539_RS05410 (F1539_05415)	-	1029881..1030087 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
F1539_RS05415 (F1539_05420)	-	1030173..1030379 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
F1539_RS05420 (F1539_05425)	-	1030453..1030659 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
F1539_RS05425 (F1539_05430)	-	1030733..1030939 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-
F1539_RS05430 (F1539_05435)	-	1031013..1031219 (+)	207	WP_005666693.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26800.82 Da
• Isoelectric Point: 8.8532

>NTDB_id=385839 F1539_RS05385 WP_013525531.1 1026550..1027242(+) (pilD) [Haemophilus influenzae biotype aegyptius strain HE24/F3037]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIQLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide

• Length: 693 bp

>NTDB_id=385839 F1539_RS05385 WP_013525531.1 1026550..1027242(+) (pilD) [Haemophilus influenzae biotype aegyptius strain HE24/F3037]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACAATCGGTTTATTTGGGGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCAGTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (92-199)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Haemophilus influenzae 86-028NP	90.435	100	0.904
pilD	Haemophilus influenzae Rd KW20	90	100	0.9