Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FY406_RS04450 Genome accession   NZ_CP043405
Coordinates   910093..910782 (+) Length   229 a.a.
NCBI ID   WP_003086734.1    Uniprot ID   A0A7X9LFL8
Organism   Streptococcus ratti strain ATCC 31377     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 905093..915782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS10405 - 906155..906277 (+) 123 Protein_832 energy-coupling factor transporter transmembrane protein EcfT -
  FY406_RS04430 (FY406_04430) rsmG 906477..907190 (-) 714 WP_003086738.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FY406_RS04435 (FY406_04435) - 907276..907836 (+) 561 WP_003086737.1 LemA family protein -
  FY406_RS04440 (FY406_04440) htpX 907846..908745 (+) 900 WP_003086736.1 zinc metalloprotease HtpX -
  FY406_RS04445 (FY406_04445) - 909200..909736 (+) 537 WP_003086735.1 DUF177 domain-containing protein -
  FY406_RS04450 (FY406_04450) covR 910093..910782 (+) 690 WP_003086734.1 response regulator transcription factor Regulator
  FY406_RS04455 (FY406_04455) nrdR 910948..911439 (+) 492 WP_003086732.1 transcriptional regulator NrdR -
  FY406_RS04460 (FY406_04460) - 911426..912592 (+) 1167 WP_003086730.1 DnaD domain protein -
  FY406_RS04465 (FY406_04465) dnaI 912593..913495 (+) 903 WP_003086728.1 primosomal protein DnaI -
  FY406_RS04470 (FY406_04470) der 913508..914818 (+) 1311 WP_003086718.1 ribosome biogenesis GTPase Der -
  FY406_RS10410 - 915168..915335 (-) 168 WP_003086716.1 hypothetical protein -
  FY406_RS04475 (FY406_04475) - 915361..915642 (-) 282 WP_003086714.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26572.50 Da        Isoelectric Point: 5.2665

>NTDB_id=383576 FY406_RS04450 WP_003086734.1 910093..910782(+) (covR) [Streptococcus ratti strain ATCC 31377]
MAKSILIIEDEKNLAKFVSLELQHEGYEVDVEHDGRSGLDKALERDFDLILLDLMLPKMDGYEVTRRLQLEKTTYIIMVT
ARDSTMDIVTGLDRGADGYVIKPFAIEELLARVRAIFRRQDIERAKHSVKKDSAYRDLQLDVHNRAAIRSGETIPLTKRE
FDLLSALMENINQVMTREELLDRVWKYDQEAETNVVDVYIRYLRGKIDVSGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=383576 FY406_RS04450 WP_003086734.1 910093..910782(+) (covR) [Streptococcus ratti strain ATCC 31377]
ATGGCTAAAAGTATTTTAATTATTGAAGATGAAAAAAACCTTGCAAAGTTTGTTTCTCTGGAACTGCAGCATGAAGGATA
TGAAGTTGACGTGGAACACGATGGACGTTCCGGCTTAGACAAAGCTCTTGAAAGGGATTTTGATTTAATCCTTCTTGATT
TGATGTTGCCGAAAATGGACGGCTATGAAGTAACGCGTCGGCTGCAGCTGGAAAAAACAACCTATATCATTATGGTTACT
GCCCGTGATTCTACTATGGATATTGTCACGGGATTGGATCGCGGTGCAGACGGCTATGTTATAAAACCTTTTGCTATTGA
AGAATTGCTGGCTCGGGTTCGCGCCATTTTTCGCCGTCAGGATATTGAAAGGGCGAAGCATTCTGTAAAGAAAGACAGTG
CTTATCGTGATTTGCAGCTGGATGTGCACAATCGAGCTGCGATTCGAAGTGGTGAAACTATACCTTTAACCAAGCGAGAG
TTTGATTTGCTCAGTGCTCTTATGGAAAACATCAACCAAGTTATGACCAGAGAAGAGCTTCTGGATCGAGTCTGGAAGTA
TGATCAAGAGGCTGAAACGAACGTGGTTGATGTCTATATTCGCTACCTTCGCGGCAAAATTGATGTCTCTGGCAAAGAAA
GTTATATTCAGACCGTCCGCGGTATGGGTTACGTTATCCGCGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7X9LFL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.856

100

0.769
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.043

100

0.633
  vicR Streptococcus mutans UA159

43.348

100

0.441
  micA Streptococcus pneumoniae Cp1015

41.558

100

0.419

Multiple sequence alignment